Discovery of a Proteolysis Targeting Chimera for TRKA and RET-derived oncoproteins

M Marialuisa Moccia L Lingzhi Zhang Z Zhengyu Wang (School of Clinical Medicine, Shandong Second Medical University) M Minmin Wang G Giorgia Federico M Massimo Santoro H Hong-Yu Li (Department of Anesthesiology, The First Affiliated Hospital of University of Science and Technology of China, Center for Advance Interdisciplinary Science and Biomedicine of Institute of Health and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China) F Francesca Carlomagno (Institute of Endotypes in Oncology, Metabolism and Immunology “G. Salvatore,” National Research Council of Italy)

Article Details

Volume / Issue Vol. 15, Issue 1
Published November 25, 2025
ISSN 2045-2322
Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (8)

M

Marialuisa Moccia

L

Lingzhi Zhang

Z

Zhengyu Wang

School of Clinical Medicine, Shandong Second Medical University

M

Minmin Wang

G

Giorgia Federico

M

Massimo Santoro

H

Hong-Yu Li

Department of Anesthesiology, The First Affiliated Hospital of University of Science and Technology of China, Center for Advance Interdisciplinary Science and Biomedicine of Institute of Health and Medicine, Hefei National Laboratory for Physical Sciences at the Microscale, Division of Life Sciences and Medicine, University of Science and Technology of China

F

Francesca Carlomagno

Institute of Endotypes in Oncology, Metabolism and Immunology “G. Salvatore,” National Research Council of Italy