Decoding health disparities by gender, ethnicity and chronic diseases across three Latin American countries

C Carlos Chivardi A Alejandro Zamudio Sosa D Daniella Medeiros Cavalcanti J José Alejandro Ordoñez C Cristina Almeida P Philipp Hessel A Ana L. Moncayo D Davide Rasella

Abstract

Abstract Chronic diseases disproportionately affect certain ethnic and gender groups, but the social determinants driving these disparities in Latin America are not fully understood. In this study, we analyzed data from national health surveys in Brazil, Mexico, and Ecuador (2018–2019), representing a total weighted population of 96,726,891 adults. We used random forest models to predict chronic disease diagnoses based on education, occupation, and access to essential services such as sanitation, drinking water, and garbage collection. Our models performed better for indigenous and afro-descendant people, highlighting significant inequalities. While occupation and education were strong predictors for women, decreasing model performance by 8.57% and 7.36% respectively, occupation was the critical variable for men, decreasing model performance by 19.6% when neutralized. This work highlights the need for public policies adapted to the specific needs of different ethnic and gender groups.

Article Details

Volume / Issue Vol. 17, Issue 1
Published February 27, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (8)

C

Carlos Chivardi

A

Alejandro Zamudio Sosa

D

Daniella Medeiros Cavalcanti

J

José Alejandro Ordoñez

C

Cristina Almeida

P

Philipp Hessel

A

Ana L. Moncayo

D

Davide Rasella