Decoding Arginine Dimethylation Isomers via pH-Tuned Reactivity with Methylglyoxal: A Chemical Approach for Functional Proteomics

J Jiayi Wang Y Ye Liu Q Qi Wang Y Yanni Ma (State Key Laboratory of Medical Proteomics, National Chromatographic R&A Center, CAS Key Laboratory of Separation Science for Analytical Chemistry) L Longrun Shi (State Key Laboratory of Medical Proteomics, National Chromatographic R&A Center, CAS Key Laboratory of Separation Science for Analytical Chemistry) Y Yan Wang Z Zhouxian Li Z Zheng Fang Z Zhen Liu J Jiayang Yan (State Key Laboratory of Medical Proteomics, National Chromatographic R&A Center, CAS Key Laboratory of Separation Science for Analytical Chemistry) X Xia Mu (State Key Laboratory of Chemical Reaction Dynamics) G Guohui Li (Interdisciplinary Research Center for Biology and Chemistry) A Anhui Wang (Interdisciplinary Research Center for Biology and Chemistry) K Keyun Wang (State Key Laboratory of Medical Proteomics, National Chromatographic R&A Center, CAS Key Laboratory of Separation Science for Analytical Chemistry) M Mingliang Ye (State Key Laboratory of Medical Proteomics, National Chromatographic R&A Center, CAS Key Laboratory of Separation Science for Analytical Chemistry)

Article Details

Volume / Issue Vol. 147, Issue 47
Published November 26, 2025
Pages 43773-43784
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (15)

J

Jiayi Wang

Y

Ye Liu

Q

Qi Wang

Y

Yanni Ma

State Key Laboratory of Medical Proteomics, National Chromatographic R&A Center, CAS Key Laboratory of Separation Science for Analytical Chemistry

L

Longrun Shi

State Key Laboratory of Medical Proteomics, National Chromatographic R&A Center, CAS Key Laboratory of Separation Science for Analytical Chemistry

Y

Yan Wang

Z

Zhouxian Li

Z

Zheng Fang

Z

Zhen Liu

J

Jiayang Yan

State Key Laboratory of Medical Proteomics, National Chromatographic R&A Center, CAS Key Laboratory of Separation Science for Analytical Chemistry

X

Xia Mu

State Key Laboratory of Chemical Reaction Dynamics

G

Guohui Li

Interdisciplinary Research Center for Biology and Chemistry

A

Anhui Wang

Interdisciplinary Research Center for Biology and Chemistry

K

Keyun Wang

State Key Laboratory of Medical Proteomics, National Chromatographic R&A Center, CAS Key Laboratory of Separation Science for Analytical Chemistry

M

Mingliang Ye

State Key Laboratory of Medical Proteomics, National Chromatographic R&A Center, CAS Key Laboratory of Separation Science for Analytical Chemistry