Deciphering the Thiolactonization Mechanism in Thiolactomycin Biosynthesis

J Jiawei Guo (Department of Chemical Engineering) Q Qiaoyu Zhang (State Key Laboratory of Physical Chemistry of Solid Surfaces and Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, College of Chemistry and Chemical Engineering) Y Yang Shen (Beijing National Laboratory for Condensed Matter Physics, Institute of Physics) F Fangyuan Cheng (State Key Laboratory of Microbial Technology) M Moli Sang (State Key Laboratory of Microbial Technology) X Xuan Wang Y Yunjun Pan M Mingyu Liu (State Key Laboratory of Microbial Technology) H Hao-Bing Yu (Department of Marine Biomedicine and Polar Medicine, Naval Medical Center) B Bo Hu S Sheng Wang L Liangzhen Zheng (Shanghai Zelixir Biotech Company Ltd.) C Ce Geng (Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology) C Chaofan Yang (State Key Laboratory of Microbial Technology) L Lianzhong Luo (Xiamen Key Laboratory of Marine Natural Product Resources) G Gang Zhang L Lei Du (State Key Laboratory of Microbial Technology) Y Yuanning Li (State Key Laboratory of Microbial Technology) W Wei Zhang Y Yandong Zhang (State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province, iCHEM, College of Chemistry and Chemical Engineering) B Binju Wang (State Key Laboratory of Physical Chemistry of Solid Surfaces and Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, College of Chemistry and Chemical Engineering) S Shengying Li X Xingwang Zhang (Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering)

Article Details

Volume / Issue Vol. 147, Issue 26
Published July 02, 2025
Pages 22368-22386
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (23)

J

Jiawei Guo

Department of Chemical Engineering

Q

Qiaoyu Zhang

State Key Laboratory of Physical Chemistry of Solid Surfaces and Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, College of Chemistry and Chemical Engineering

Y

Yang Shen

Beijing National Laboratory for Condensed Matter Physics, Institute of Physics

F

Fangyuan Cheng

State Key Laboratory of Microbial Technology

M

Moli Sang

State Key Laboratory of Microbial Technology

X

Xuan Wang

Y

Yunjun Pan

M

Mingyu Liu

State Key Laboratory of Microbial Technology

H

Hao-Bing Yu

Department of Marine Biomedicine and Polar Medicine, Naval Medical Center

B

Bo Hu

S

Sheng Wang

L

Liangzhen Zheng

Shanghai Zelixir Biotech Company Ltd.

C

Ce Geng

Shandong Provincial Key Laboratory of Synthetic Biology, Qingdao Institute of Bioenergy and Bioprocess Technology

C

Chaofan Yang

State Key Laboratory of Microbial Technology

L

Lianzhong Luo

Xiamen Key Laboratory of Marine Natural Product Resources

G

Gang Zhang

L

Lei Du

State Key Laboratory of Microbial Technology

Y

Yuanning Li

State Key Laboratory of Microbial Technology

W

Wei Zhang

Y

Yandong Zhang

State Key Laboratory of Physical Chemistry of Solid Surfaces, Key Laboratory of Chemical Biology of Fujian Province, iCHEM, College of Chemistry and Chemical Engineering

B

Binju Wang

State Key Laboratory of Physical Chemistry of Solid Surfaces and Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, College of Chemistry and Chemical Engineering

S

Shengying Li

X

Xingwang Zhang

Key Laboratory of Biomass Chemical Engineering of Ministry of Education, College of Chemical and Biological Engineering