Data-Driven Design of Random Heteropolypeptides as Synthetic Polyclonal Antibodies

H Haisen Zhou (Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering) G Guangqi Wu (Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering) Z Zuo Zhang (Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Key Laboratory of Polymer Chemistry & Physics, National Biomedical Imaging Center) Z Zhen Zhu (Academy for Advanced Interdisciplinary Studies) T Tanfeng Zhao (State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering) Q Qiankang Zhou (Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering) H Haolin Chen (Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering) Z Zhenzhong Zhao (Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering) Y Yuanhao Dai (Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering) X Xiaodong Jing (Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering) W Wei Ji (Beijing Key Laboratory of Optoelectronic Functional Materials & Micro-Nano Devices, School of Physics) X Xuehai Yan (State Key Laboratory of Biopharmaceutical Preparation and Delivery) L Lijiang Yang (Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering) Y Yiqin Gao (Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering) H Huan Wang H Hua Lu (Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering)

Article Details

Volume / Issue Vol. 147, Issue 24
Published June 18, 2025
Pages 21077-21088
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (16)

H

Haisen Zhou

Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering

G

Guangqi Wu

Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering

Z

Zuo Zhang

Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering, Key Laboratory of Polymer Chemistry & Physics, National Biomedical Imaging Center

Z

Zhen Zhu

Academy for Advanced Interdisciplinary Studies

T

Tanfeng Zhao

State Key Laboratory of Biopharmaceutical Preparation and Delivery, Institute of Process Engineering

Q

Qiankang Zhou

Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering

H

Haolin Chen

Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering

Z

Zhenzhong Zhao

Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering

Y

Yuanhao Dai

Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering

X

Xiaodong Jing

Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering

W

Wei Ji

Beijing Key Laboratory of Optoelectronic Functional Materials & Micro-Nano Devices, School of Physics

X

Xuehai Yan

State Key Laboratory of Biopharmaceutical Preparation and Delivery

L

Lijiang Yang

Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering

Y

Yiqin Gao

Beijing National Laboratory for Molecular Sciences, College of Chemistry and Molecular Engineering

H

Huan Wang

H

Hua Lu

Beijing National Laboratory for Molecular Sciences, Center for Soft Matter Science and Engineering, Key Laboratory of Polymer Chemistry and Physics of Ministry of Education, College of Chemistry and Molecular Engineering