CXC Chemokine Ligand 12 Facilitates Gi Protein Binding to CXC Chemokine Receptor 4 by Stabilizing Packing of the Proline–Isoleucine–Phenylalanine Motif: Insights from Automated Path Searching

X Xinyu Li (Cell and Molecular Biology Program) Y Yezhou Liu (Kobilka Institute of Innovative Drug Discovery, School of Medicine) J Jinchu Liu (School of Medicine and Warshel Institute for Computational Biology) W Wenzhuo Ma (School of Medicine and Warshel Institute for Computational Biology) R Rujuan Ti (School of Medicine and Warshel Institute for Computational Biology) A Arieh Warshel (Department of Chemistry) R Richard D. Ye (Kobilka Institute of Innovative Drug Discovery, School of Medicine) L Lizhe Zhu (School of Medicine and Warshel Institute for Computational Biology)

Article Details

Volume / Issue Vol. 147, Issue 12
Published March 26, 2025
Pages 10129-10138
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (8)

X

Xinyu Li

Cell and Molecular Biology Program

Y

Yezhou Liu

Kobilka Institute of Innovative Drug Discovery, School of Medicine

J

Jinchu Liu

School of Medicine and Warshel Institute for Computational Biology

W

Wenzhuo Ma

School of Medicine and Warshel Institute for Computational Biology

R

Rujuan Ti

School of Medicine and Warshel Institute for Computational Biology

A

Arieh Warshel

Department of Chemistry

R

Richard D. Ye

Kobilka Institute of Innovative Drug Discovery, School of Medicine

L

Lizhe Zhu

School of Medicine and Warshel Institute for Computational Biology