Cultivated autologous limbal epithelial cell (CALEC) transplantation for limbal stem cell deficiency: a phase I/II clinical trial of the first xenobiotic-free, serum-free, antibiotic-free manufacturing protocol developed in the US

Ula V. Jurkunas; Aaron R. Kaufman; Jia Yin; Allison Ayala; Maureen Maguire; Lassana Samarakoon; Lynette K. Johns; Mohit Parekh; Sanming Li; Alex Gauthier; Helene Negre; Kit L. Shaw; Diego E. Hernandez Rodriguez; Heather Daley; Reza Dana; Myriam Armant; Jerome Ritz

doi:10.1038/s41467-025-56461-1

Cultivated autologous limbal epithelial cell (CALEC) transplantation for limbal stem cell deficiency: a phase I/II clinical trial of the first xenobiotic-free, serum-free, antibiotic-free manufacturing protocol developed in the US

U Ula V. Jurkunas A Aaron R. Kaufman J Jia Yin A Allison Ayala M Maureen Maguire L Lassana Samarakoon L Lynette K. Johns M Mohit Parekh S Sanming Li A Alex Gauthier H Helene Negre K Kit L. Shaw D Diego E. Hernandez Rodriguez H Heather Daley R Reza Dana M Myriam Armant J Jerome Ritz (Dana–Farber Cancer Institute, Boston)

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Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published March 04, 2025

DOI 10.1038/s41467-025-56461-1

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (17)

U

Ula V. Jurkunas

A

Aaron R. Kaufman

J

Jia Yin

A

Allison Ayala

M

Maureen Maguire

L

Lassana Samarakoon

L

Lynette K. Johns

M

Mohit Parekh

S

Sanming Li

A

Alex Gauthier

H

Helene Negre

K

Kit L. Shaw

D

Diego E. Hernandez Rodriguez

H

Heather Daley

R

Reza Dana

M

Myriam Armant

J

Jerome Ritz

Dana–Farber Cancer Institute, Boston

Cultivated autologous limbal epithelial cell (CALEC) transplantation for limbal stem cell deficiency: a phase I/II clinical trial of the first xenobiotic-free, serum-free, antibiotic-free manufacturing protocol developed in the US

Article Details

Journal Info

Authors (17)

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