Cross-dataset pan-cancer detection by correlating cell-free DNA fragment coverage with open chromatin sites across cell types

Ludvig Renbo Olsen; Denis Odinokov; Jakob Qvortrup Holsting; Karoline Kondrup; Laura Iisager; Maria Rusan; Simon Buus; Britt Elmedal Laursen; Michael Borre; Mads Ryø Jochumsen; Kirsten Bouchelouche; Amanda Frydendahl; Mads Heilskov Rasmussen; Tenna Vesterman Henriksen; Marijana Nesic; Christina Demuth; Sia Viborg Lindskrog; Iver Nordentoft; Philippe Lamy; Christina Therkildsen; Lars Dyrskjøt; Karina Dalsgaard Sørensen; Claus Lindbjerg Andersen; Anders Jakobsen Skanderup; Søren Besenbacher

doi:10.1038/s41467-025-66503-3

Cross-dataset pan-cancer detection by correlating cell-free DNA fragment coverage with open chromatin sites across cell types

L Ludvig Renbo Olsen D Denis Odinokov J Jakob Qvortrup Holsting K Karoline Kondrup L Laura Iisager M Maria Rusan S Simon Buus B Britt Elmedal Laursen M Michael Borre M Mads Ryø Jochumsen K Kirsten Bouchelouche A Amanda Frydendahl M Mads Heilskov Rasmussen T Tenna Vesterman Henriksen M Marijana Nesic C Christina Demuth S Sia Viborg Lindskrog I Iver Nordentoft P Philippe Lamy C Christina Therkildsen L Lars Dyrskjøt K Karina Dalsgaard Sørensen C Claus Lindbjerg Andersen A Anders Jakobsen Skanderup S Søren Besenbacher

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Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published November 21, 2025

DOI 10.1038/s41467-025-66503-3

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (25)

L

Ludvig Renbo Olsen

D

Denis Odinokov

J

Jakob Qvortrup Holsting

K

Karoline Kondrup

L

Laura Iisager

M

Maria Rusan

S

Simon Buus

B

Britt Elmedal Laursen

M

Michael Borre

M

Mads Ryø Jochumsen

K

Kirsten Bouchelouche

A

Amanda Frydendahl

M

Mads Heilskov Rasmussen

T

Tenna Vesterman Henriksen

M

Marijana Nesic

C

Christina Demuth

S

Sia Viborg Lindskrog

I

Iver Nordentoft

P

Philippe Lamy

C

Christina Therkildsen

L

Lars Dyrskjøt

K

Karina Dalsgaard Sørensen

C

Claus Lindbjerg Andersen

A

Anders Jakobsen Skanderup

S

Søren Besenbacher

Cross-dataset pan-cancer detection by correlating cell-free DNA fragment coverage with open chromatin sites across cell types

Article Details

Journal Info

Authors (25)

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