Crocetin curbs radiation induced intestinal injury by blocking KAT2A/NLRP3 succinylation

H He Chen (Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, Tisch Cancer Institute) Y Yanping Wang (Zhejiang Engineering Research Center for Biological Control of Crop Pathogens and Insects, Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Ministry of Agriculture and Rural Affairs Key Lab of Molecular Biology of Crop Pathogens and Insect Pests, State Key Lab of Rice Biology and Breeding, Institute of Insect Sciences, College of Agriculture and Biotechnology, Zhejiang University) Y Yi Xu F Fu Liu (New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute) Q Quanxiao Xu L Lei Dong (Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.) C Changxiang Yang X Xu Xie J Jincong Yang X Xinping Zhang

Article Details

Volume / Issue Vol. 15, Issue 1
Published October 21, 2025
ISSN 2045-2322
Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (10)

H

He Chen

Mount Sinai Center for Therapeutics Discovery, Departments of Pharmacological Sciences, Oncological Sciences and Neuroscience, Tisch Cancer Institute

Y

Yanping Wang

Zhejiang Engineering Research Center for Biological Control of Crop Pathogens and Insects, Zhejiang Key Laboratory of Biology and Ecological Regulation of Crop Pathogens and Insects, Ministry of Agriculture and Rural Affairs Key Lab of Molecular Biology of Crop Pathogens and Insect Pests, State Key Lab of Rice Biology and Breeding, Institute of Insect Sciences, College of Agriculture and Biotechnology, Zhejiang University

Y

Yi Xu

F

Fu Liu

New Cornerstone Science Laboratory, Shenzhen Grubbs Institute, Department of Chemistry, and Guangming Advanced Research Institute

Q

Quanxiao Xu

L

Lei Dong

Quantitative Biomedical Research Center, University of Texas Southwestern Medical Center, Dallas, TX, USA.

C

Changxiang Yang

X

Xu Xie

J

Jincong Yang

X

Xinping Zhang