Critique of enhanced power claimed for Quasi-ANCOVA and Dual-Centered ANCOVA

B B. Wade Brorsen H Hua Lin R Robert E. Larzelere

Abstract

Two related methods, Quasi-ANCOVA and Dual-Centered ANCOVA, have recently been suggested as a way to get greater power when analyzing data from a before and after study. Both methods use group-mean centering where the groups are the treatment and comparison groups. Group-mean centering creates a generated regressor problem. When the estimated standard errors are corrected for the generated regressor problem, there is no longer any gain in power. The corrected Quasi-ANCOVA estimates are identical to those from ANOVA and the corrected Dual-Centered ANCOVA estimates are identical to those from the differences model. These conclusions are derived analytically and also verified using a Monte Carlo simulation.

Article Details

Journal PLoS ONE
Volume / Issue Vol. 20, Issue 1
Published January 22, 2025
Pages e0317860
ISSN 1932-6203
Publisher Public Library of Science

Journal Info

PLoS ONE

Public Library of Science

ISSN: 1932-6203 Open Access Health Sciences

Authors (3)

B

B. Wade Brorsen

H

Hua Lin

R

Robert E. Larzelere