Journal of the American Chemical Society

Creating a Modular Activatable CRISPR–Cas12a System by Engineering crRNA Scaffold with a Steric Hindrance Effector

P Pengfei Liu S Sheng Li J Jiayu Zeng (Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, Institute of Interdisciplinary Studies, College of Chemistry and Chemical Engineering) M Meixia Wang (State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, College of Chemistry and Chemical Engineering, College of Biology) J Jinlian Du (Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, Institute of Interdisciplinary Studies, College of Chemistry and Chemical Engineering) H Hong-Hui Wang (State Key Laboratory of Chemo and Biosensing, College of Biology, College of Chemistry and Chemical Engineering) E Erhu Xiong (Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, Institute of Interdisciplinary Studies, College of Chemistry and Chemical Engineering) R Ronghua Yang (Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, Institute of Interdisciplinary Studies, College of Chemistry and Chemical Engineering)
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Article Details

Volume / Issue Vol. 147, Issue 34
Published August 27, 2025
Pages 31349-31364
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society
ISSN: 0002-7863 Physical Sciences

Authors (8)

P

Pengfei Liu

S

Sheng Li

J

Jiayu Zeng

Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, Institute of Interdisciplinary Studies, College of Chemistry and Chemical Engineering

M

Meixia Wang

State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan Provincial Key Laboratory of Biomacromolecular Chemical Biology, College of Chemistry and Chemical Engineering, College of Biology

J

Jinlian Du

Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, Institute of Interdisciplinary Studies, College of Chemistry and Chemical Engineering

H

Hong-Hui Wang

State Key Laboratory of Chemo and Biosensing, College of Biology, College of Chemistry and Chemical Engineering

E

Erhu Xiong

Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, Institute of Interdisciplinary Studies, College of Chemistry and Chemical Engineering

R

Ronghua Yang

Key Laboratory of Chemical Biology & Traditional Chinese Medicine Research, Ministry of Education, Institute of Interdisciplinary Studies, College of Chemistry and Chemical Engineering

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