Convergent Total Synthesis of Papililone A via Pd-Catalyzed Alkenylation/Cyclization Cascade

X Xing-Qian Shan (School of Pharmaceutical Sciences, Shanghai Key Laboratory of Chiral Drugs and Engineering, Shanghai Frontiers Science Center of Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy) X Xiang Zhang P Peng-Fei Lian (School of Pharmaceutical Sciences, Shanghai Key Laboratory of Chiral Drugs and Engineering, Shanghai Frontiers Science Center of Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy) B Bao-Kuan Guo (School of Pharmaceutical Sciences, School of Chemistry and Chemical Engineering, School of Artificial Intelligence, Frontier Scientific Center of Transformative Molecules, National Key Laboratory of Innovative Immunotherapy, MoE Key Laboratory of Artificial Intelligence) Y Yong-Qiang Tu (State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering) S Si-Hua Hou (School of Pharmaceutical Sciences, Shanghai Key Laboratory of Chiral Drugs and Engineering, Shanghai Frontiers Science Center of Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy)

Article Details

Volume / Issue Vol. 147, Issue 49
Published December 10, 2025
Pages 44714-44719
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (6)

X

Xing-Qian Shan

School of Pharmaceutical Sciences, Shanghai Key Laboratory of Chiral Drugs and Engineering, Shanghai Frontiers Science Center of Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy

X

Xiang Zhang

P

Peng-Fei Lian

School of Pharmaceutical Sciences, Shanghai Key Laboratory of Chiral Drugs and Engineering, Shanghai Frontiers Science Center of Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy

B

Bao-Kuan Guo

School of Pharmaceutical Sciences, School of Chemistry and Chemical Engineering, School of Artificial Intelligence, Frontier Scientific Center of Transformative Molecules, National Key Laboratory of Innovative Immunotherapy, MoE Key Laboratory of Artificial Intelligence

Y

Yong-Qiang Tu

State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering

S

Si-Hua Hou

School of Pharmaceutical Sciences, Shanghai Key Laboratory of Chiral Drugs and Engineering, Shanghai Frontiers Science Center of Drug Target Identification and Delivery, National Key Laboratory of Innovative Immunotherapy