Journal of Clinical Oncology

Colorectal-Specific Radiation Dose and Chemotherapy Risk for Subsequent Colorectal Malignancies in Childhood Cancer Survivors: A Childhood Cancer Survivor Study (CCSS) Report

C Constance A. Owens (Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...) E Ethan B. Ludmir (Noah S. Meimoun, BA, Division of Radiation Oncology, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX; Alexander D. Sherry, MD, Department of Radiation Oncology, The Mayo Clinic, Rochester, MN; Ethan B. Ludmir, MD, Division of Radiation Oncology, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX; and Timothy A. Lin, MD, MBA, Division of Radiation Oncology, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX) Q Qi Liu W Weiyu Qiu A Aashish C. Gupta (Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...) S Susan A. Smith (Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...) B Bastien Rigaud (Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...) K Kristy K. Brock J James E. Bates T Taylor G. Meyers (Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...) A Arnold C. Paulino (Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...) C Christine B. Peterson (The University of Texas MD Anderson Cancer Center, Houston, TX) S Stephen F. Kry (The University of Texas MD Anderson Cancer Center, Houston, TX) J Jop C. Teepen (Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...) C Cecile M. Ronckers (Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...) J Joseph P. Neglia W Wendy M. Leisenring (Fred Hutchinson Cancer Center, Seattle, WA) K Kevin C. Oeffinger (DCI Center for Onco‐Primary Care Duke University Durham North Carolina USA) P Paul C. Nathan L Lucie M. Turcotte D David C. Hodgson (Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...) M Melissa M. Hudson L Leslie L. Robison C Chaya S. Moskowitz G Gregory T. Armstrong T Tara O. Henderson Y Yutaka Yasui R Rebecca M. Howell

Abstract

PURPOSE Among childhood cancer survivors, we evaluated not previously explored relationships between colorectal subsequent malignant neoplasm (SMN) incidence and colorectum-specific radiation dose metrics currently used in radiation therapy (RT) planning and expanded upon previously reported chemotherapy associations. METHODS The Childhood Cancer Survivor Study (CCSS) includes 5-year survivors of childhood cancer diagnosed between 1970 and 1999. RT was assessed as mean colorectal dose (MCD) and the percent volume (V X Gy ) receiving ≥5, 10, 20, 30, and 40 Gy. Chemotherapy was assessed as cumulative doses for procarbazine and platinum agents, cyclophosphamide-equivalent doses for alkylating agents, and doxorubicin-equivalent doses for anthracyclines. Piecewise-exponential models and excess rate ratio (ERR) models evaluated dose-response relationships for the incidence of colorectal SMNs. Reference groups were those not receiving the assessed treatment(s). RESULTS Among 25,723 survivors (median follow-up = 28.5 years; range = 5.0-48.9), 104 colorectal SMNs were identified. A dose-response relationship was observed between MCD and colorectal SMN rates; incidence rate ratios (IRRs) for 10 to <20 Gy and ≥20 Gy were 3.6 (95% CI, 1.9 to 6.9) and 8.3 (95% CI, 3.9 to 17.8), respectively. When ≥20% of the colorectum volume was irradiated, IRRs increased with increasing volume. The V 20 Gy IRRs were 3.8 (95% CI, 1.9 to 7.6), 4.9 (95% CI, 2.0 to 12.0), and 8.7 (95% CI, 3.5 to 21.6) for irradiated volumes of 20% to <40%, 40% to <80%, and ≥80%, respectively. The IRR was 1.8 (95% CI, 1.0 to 3.0) for doxorubicin-equivalent dose ≥250 mg/m 2 , 3.7 (95% CI, 2.2 to 6.4) for cyclophosphamide-equivalent dose ≥6,000 mg/m 2 , and 4.5 (95% CI, 2.0 to 10.1) for platinum dose ≥450 mg/m 2 . For procarbazine dose, the IRR was 6.3 (95% CI, 3.0 to 13.2) for 4,200 to <7,036 mg/m 2 and 9.0 (95% CI, 4.3 to 18.9) for ≥7,036 mg/m 2 . In the absence of RT, colorectal SMN rates increased with exposure to any platinum-based agent (IRR, 3.8 [95% CI, 1.1 to 12.7]), alkylator (IRR, 4.8 [95% CI, 1.6 to 14.4]), or procarbazine (IRR, 16.9 [95% CI, 5.9 to 48.8]). Colorectal SMN rates increased linearly with procarbazine dose (ERR per 1,000 mg/m 2 = 73.0 [95% CI, 26.4% to 119.6%]) and MCD (ERR per 1 Gy = 20.8 [95% CI, 9.0% to 32.5%]). Quadratic ERR models did not improve data fit compared with linear ERR models. CONCLUSION These RT and chemotherapy dose-response relationships can better inform contemporary RT planning for pediatric patients and surveillance guidelines for high-risk survivors.

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Article Details

Volume / Issue Vol. 43, Issue 31
Published November 01, 2025
Pages 3403-3421
ISSN 0732-183X
Publisher Lippincott Williams & Wilkins

Journal Info

Journal of Clinical Oncology

Lippincott Williams & Wilkins
ISSN: 0732-183X Health Sciences

Authors (28)

C

Constance A. Owens

Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...

E

Ethan B. Ludmir

Noah S. Meimoun, BA, Division of Radiation Oncology, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX; Alexander D. Sherry, MD, Department of Radiation Oncology, The Mayo Clinic, Rochester, MN; Ethan B. Ludmir, MD, Division of Radiation Oncology, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX; and Timothy A. Lin, MD, MBA, Division of Radiation Oncology, Department of Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX

Q

Qi Liu

W

Weiyu Qiu

A

Aashish C. Gupta

Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...

S

Susan A. Smith

Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...

B

Bastien Rigaud

Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...

K

Kristy K. Brock

J

James E. Bates

T

Taylor G. Meyers

Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...

A

Arnold C. Paulino

Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...

C

Christine B. Peterson

The University of Texas MD Anderson Cancer Center, Houston, TX

S

Stephen F. Kry

The University of Texas MD Anderson Cancer Center, Houston, TX

J

Jop C. Teepen

Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...

C

Cecile M. Ronckers

Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...

J

Joseph P. Neglia

W

Wendy M. Leisenring

Fred Hutchinson Cancer Center, Seattle, WA

K

Kevin C. Oeffinger

DCI Center for Onco‐Primary Care Duke University Durham North Carolina USA

P

Paul C. Nathan

L

Lucie M. Turcotte

D

David C. Hodgson

Constance A. Owens, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Ethan B. Ludmir, MD, Department of Gastrointestinal Radiation Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX; Qi Liu, PhD, and Weiyu Qiu, PhD, Department of Public Health Sciences, University of Alberta, Edmonton, AB, Canada; Aashish C. Gupta, MS, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Susan A. Smith, MPH, and Bastien Rigaud, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; Kristy K. Brock, PhD, Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, Department of Imaging Physics, The University of Texas MD Anderson Cancer Center, Houston, TX; James E. Bates, MD, Department of Radiation Oncology, Winship Cancer Institute, ...

M

Melissa M. Hudson

L

Leslie L. Robison

C

Chaya S. Moskowitz

G

Gregory T. Armstrong

T

Tara O. Henderson

Y

Yutaka Yasui

R

Rebecca M. Howell

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