Clustering matrix-object data by correlational structure as proxy causal signals

Z Ziheng Qi (School of Chemistry and Molecular Engineering) L Liqin Yu J Junfei Li

Abstract

Abstract Matrix-object clustering addresses samples with multiple records per object. Many existing methods overlook within-object dependencies, which reduces interpretability and mixes heterogeneous regimes. We propose a clustering approach that uses intra-object correlational structure as a proxy for causal signals to separate regimes prior to any formal causal discovery. Each object is transformed into a rank-based correlation representation, enabling standard distance-based clustering while preserving interpretability. On synthetic and real-world datasets, the method yields stable, interpretable clusters that reduce regime mixing. We emphasize the boundary that correlation does not imply causation; correlational patterns are used only as proxy signals under the stated assumptions.

Article Details

Volume / Issue Vol. 1, Issue 1
Published July 10, 2026
ISSN 2045-2322
Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (3)

Z

Ziheng Qi

School of Chemistry and Molecular Engineering

L

Liqin Yu

J

Junfei Li