Chenodeoxycholic acid modulates cholestatic niche through FXR/Myc/P-selectin axis in liver endothelial cells

Peng Zhang; Xinying Li; Jinyuan Liang; Yuanwen Zheng; Yao Tong; Jing Shen; Yatai Chen; Penghu Han; Shuzheng Chu; Ruirui Liu; Mengqi Zheng; Yunjiao Zhai; Xiaolong Tang; Cuijuan Zhang; Hui Qu; Ping Mi; Jin Chai; Detian Yuan; Shiyang Li

doi:10.1038/s41467-025-57351-2

Chenodeoxycholic acid modulates cholestatic niche through FXR/Myc/P-selectin axis in liver endothelial cells

P Peng Zhang X Xinying Li J Jinyuan Liang Y Yuanwen Zheng Y Yao Tong J Jing Shen Y Yatai Chen P Penghu Han S Shuzheng Chu R Ruirui Liu M Mengqi Zheng (Department of Chemical Physics, University of Science and Technology of China 1 , Hefei 230026,) Y Yunjiao Zhai X Xiaolong Tang C Cuijuan Zhang (School of Chemical Sciences) H Hui Qu P Ping Mi J Jin Chai D Detian Yuan S Shiyang Li

Download PDF View Original

APA MLA Chicago BibTeX RIS

Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published March 01, 2025

DOI 10.1038/s41467-025-57351-2

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (19)

P

Peng Zhang

X

Xinying Li

J

Jinyuan Liang

Y

Yuanwen Zheng

Y

Yao Tong

J

Jing Shen

Y

Yatai Chen

P

Penghu Han

S

Shuzheng Chu

R

Ruirui Liu

M

Mengqi Zheng

Department of Chemical Physics, University of Science and Technology of China 1 , Hefei 230026,

Y

Yunjiao Zhai

X

Xiaolong Tang

C

Cuijuan Zhang

School of Chemical Sciences

H

Hui Qu

P

Ping Mi

J

Jin Chai

D

Detian Yuan

S

Shiyang Li

Chenodeoxycholic acid modulates cholestatic niche through FXR/Myc/P-selectin axis in liver endothelial cells

Article Details

Journal Info

Authors (19)

Related Articles from this Journal

Synthesis of adaptive 15N-nitrosyl-Co7 nanocluster for electrocatalytic C–H functionalization

Pan-Ebolavirus nanoparticle vaccine provides protection in rodents from lethal infection by Zaire and Sudan viruses

Multi-population GWAS meta-analysis identifies bladder cancer susceptibility loci and highlights genetic regulation of smoking-related risk

Genome-wide annotation of human multi-nucleotide variants reveals widespread functional differences from single nucleotide variants

Allele-specific chromatin architecture shapes imprinted domains and coordinates a distal enhancer and antisense transcription at the mouse Mest-Copg2 domain