Chemoenzymatic Synthesis of Arisugacins and Terreulactones via Directed Evolution of a Privileged Sclareolide Dioxygenase

X Xiaotao Liu (Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, State Key Laboratory of Synergistic Chem-Bio Synthesis, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs and Zhangjiang Institute for Advanced Study) Y Yueshen Feng (Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, State Key Laboratory of Synergistic Chem-Bio Synthesis, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs and Zhangjiang Institute for Advanced Study) C Cheng Yuan (State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry) L Lingling Li (Instrumental Analysis Center) J Jian Li

Article Details

Volume / Issue Vol. 148, Issue 8
Published March 04, 2026
Pages 9031-9039
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (5)

X

Xiaotao Liu

Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, State Key Laboratory of Synergistic Chem-Bio Synthesis, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs and Zhangjiang Institute for Advanced Study

Y

Yueshen Feng

Frontiers Science Center for Transformative Molecules, School of Chemistry and Chemical Engineering, State Key Laboratory of Synergistic Chem-Bio Synthesis, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs and Zhangjiang Institute for Advanced Study

C

Cheng Yuan

State Key Laboratory of Analytical Chemistry for Life Science, School of Chemistry

L

Lingling Li

Instrumental Analysis Center

J

Jian Li