Chemical Protein Synthesis via Direction-Switching One-Pot Peptide Ligation Enabled by Orthogonal Cysteinyl Protection
K
Koki Nakatsu
(Department of Biomolecular Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan)
F
Fumika Yoshitomi
(Department of Biomolecular Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan)
H
Hiroki Onoda
R
Reia Shikimachi
K
Kyohei Arita
A
Akimitsu Okamoto
(Department of Chemistry and Biotechnology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan)
H
Hiroshi Murakami
G
Gosuke Hayashi
(Department of Biomolecular Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan)
Article Details
Volume / Issue
Vol. 148, Issue 4
Published
February 04, 2026
Pages
4622-4634
ISSN
0002-7863
Publisher
American Chemical Society
Journal Info
Journal of the American Chemical Society
American Chemical Society
ISSN: 0002-7863 Physical Sciences
Authors (8)
K
Koki Nakatsu
Department of Biomolecular Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan
F
Fumika Yoshitomi
Department of Biomolecular Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan
H
Hiroki Onoda
R
Reia Shikimachi
K
Kyohei Arita
A
Akimitsu Okamoto
Department of Chemistry and Biotechnology, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8656, Japan
H
Hiroshi Murakami
G
Gosuke Hayashi
Department of Biomolecular Engineering, Nagoya University, Furo-cho, Chikusa-ku, Nagoya 464-8603, Japan
Related Articles from this Journal
Rational Design of the Composite Perfluoro-Sulfonic Ionomer for High-Performance Proton Exchange Membrane Fuel Cells
Tingting Mao, Haiyang Fan et al.
Jul 2026
10.1021/jacs.6c05625
Ti3+-O Acid–Base Pairs for Efficient Solar-Driven Photothermal Nonoxidative Ethane Dehydrogenation
Yuwen Sun, Kun Gong et al.
Jul 2026
10.1021/jacs.6c08665
Total Synthesis of Benthol A: Evidence for a Structure Revision
Guanghao Huang, Andrea Tomio et al.
Jul 2026
10.1021/jacs.6c05580
Accelerated Self-Photopolymerization of Phenolics in Microdroplets Contributes to the Brown Carbon Formation
Haoran Yu, Xinrui Yang et al.
Jul 2026
10.1021/jacs.6c10186
Deciphering the Specificity of Reversible DNA-Phosphate ADP-Ribosylation via the Precise Synthesis and Enzymatic Profiling of Nucleotide-Phospho-ADP-Ribosyl Probes
Lingxiao Liu, Yang Lu et al.
Jul 2026
10.1021/jacs.6c02874