Journal of the American Chemical Society

Chem–Bio Hybrid Synthesis Enables Reengineering of Natural Product-Based Methionine Aminopeptidase 2 Inhibitors for Treating Amebiasis

Y Yuki Okura (Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa, Nagoya, Aichi 464-8601, Japan) Y Yumiko Saito-Nakano (Department of Parasitology) A Andrii Balia (Department of Nanopharmaceutical Sciences and Department of Life Science and Applied Chemistry) N Nurul Syahmin Binti Suhaimi (Department of Nanopharmaceutical Sciences and Department of Life Science and Applied Chemistry) C Chika Ando (Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa, Nagoya, Aichi 464-8601, Japan) N Namiko Ogata (School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan) T Tomona Ikeda (Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa, Nagoya, Aichi 464-8601, Japan) T Takumi Sato (School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan) K Keiko Kano (Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa, Nagoya, Aichi 464-8601, Japan) E Emi Mishiro-Sato (Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa, Nagoya, Aichi 464-8601, Japan) M Masaki Kita N Noriyuki Miyoshi (Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan) K Kenji Watanabe K Kouichi Yoshinari (School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan) N Norio Shibata (Department of Nanopharmaceutical Sciences and Department of Life Science and Applied Chemistry) M Mihoko Mori (Graduate School of Agriculture) S Seiki Kobayashi (Department of Parasitology) Y Yuji Sumii (Department of Nanopharmaceutical Sciences and Department of Life Science and Applied Chemistry) R Ryota Shizu (School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan) T Tomoyoshi Nozaki (Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan) Y Yuta Tsunematsu (Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 464-8601, Japan)
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Article Details

Volume / Issue Vol. 148, Issue 7
Published February 25, 2026
Pages 7189-7201
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society
ISSN: 0002-7863 Physical Sciences

Authors (21)

Y

Yuki Okura

Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa, Nagoya, Aichi 464-8601, Japan

Y

Yumiko Saito-Nakano

Department of Parasitology

A

Andrii Balia

Department of Nanopharmaceutical Sciences and Department of Life Science and Applied Chemistry

N

Nurul Syahmin Binti Suhaimi

Department of Nanopharmaceutical Sciences and Department of Life Science and Applied Chemistry

C

Chika Ando

Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa, Nagoya, Aichi 464-8601, Japan

N

Namiko Ogata

School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan

T

Tomona Ikeda

Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa, Nagoya, Aichi 464-8601, Japan

T

Takumi Sato

School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan

K

Keiko Kano

Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa, Nagoya, Aichi 464-8601, Japan

E

Emi Mishiro-Sato

Institute of Transformative Bio-Molecules (WPI-ITbM), Nagoya University, Furo-cho, Chikusa, Nagoya, Aichi 464-8601, Japan

M

Masaki Kita

N

Noriyuki Miyoshi

Graduate School of Integrated Pharmaceutical and Nutritional Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan

K

Kenji Watanabe

K

Kouichi Yoshinari

School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan

N

Norio Shibata

Department of Nanopharmaceutical Sciences and Department of Life Science and Applied Chemistry

M

Mihoko Mori

Graduate School of Agriculture

S

Seiki Kobayashi

Department of Parasitology

Y

Yuji Sumii

Department of Nanopharmaceutical Sciences and Department of Life Science and Applied Chemistry

R

Ryota Shizu

School of Pharmaceutical Sciences, University of Shizuoka, 52-1 Yada, Suruga-ku, Shizuoka 422-8526, Japan

T

Tomoyoshi Nozaki

Department of Biomedical Chemistry, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan

Y

Yuta Tsunematsu

Graduate School of Bioagricultural Sciences, Nagoya University, Furo-cho, Chikusa-ku, Nagoya, Aichi 464-8601, Japan

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