Cathepsin B protease mediates high population density-induced mutagenesis to drive genome evolution and competitive growth

B Bin Yu Y Yuji Suehiro B Bryan J. Johnson E Eui-Seung Lee (Department of Molecular, Cellular and Developmental Biology, University of Colorado) D Dongdong Li (Key Laboratory for Ultrafine Materials of Ministry of Education, Shanghai Engineering Research Center of Hierarchical Nanomaterials, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China) Y Yawen Huang J Joshua Johnson (Division of Reproductive Endocrinology and Infertility, University of Vermont Larner College of Medicine, Burlington) G Guangshuo Ou (Tsinghua-Peking Center for Life Sciences, Tsinghua University) J James DeGregori S Shohei Mitani (Department of Physiology, Tokyo Women’s Medical University School of Medicine) D Ding Xue (Department of Molecular, Cellular and Developmental Biology, University of Colorado)

Article Details

Volume / Issue Vol. 17, Issue 1
Published May 04, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (11)

B

Bin Yu

Y

Yuji Suehiro

B

Bryan J. Johnson

E

Eui-Seung Lee

Department of Molecular, Cellular and Developmental Biology, University of Colorado

D

Dongdong Li

Key Laboratory for Ultrafine Materials of Ministry of Education, Shanghai Engineering Research Center of Hierarchical Nanomaterials, School of Materials Science and Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai 200237, China

Y

Yawen Huang

J

Joshua Johnson

Division of Reproductive Endocrinology and Infertility, University of Vermont Larner College of Medicine, Burlington

G

Guangshuo Ou

Tsinghua-Peking Center for Life Sciences, Tsinghua University

J

James DeGregori

S

Shohei Mitani

Department of Physiology, Tokyo Women’s Medical University School of Medicine

D

Ding Xue

Department of Molecular, Cellular and Developmental Biology, University of Colorado