Cartilage targeting hydrogel nanoplatform degrades BRD4 to alleviate osteoarthritis via Nav1.7 axis

Q Qirui Zhao T Tongtong Xu Z Zuchao Du X Xiaoqing Lu (School of Materials Science and Engineering) Y Yan Zhang L Linjia Peng Z Zixuan Gao (Department of Chemistry) W Weicheng Wang B Binyu Zhu Z Zhigang Liu (State Key Laboratory of Chemical Biology) G Guangjie Yang H Hui Zhao (Center of Ionic Liquid and Green Energy, Beijing Key Laboratory of Solid State Battery and Energy Storage Process, State Key Laboratory of Mesoscience and Engineering, Institute of Process Engineering) Z Zhiming Song Q Qiankun Lou J Jiaming Li Z Zhiguang Ren Z Zhe Yu W Wei Wang Y Yanlei Liu H Hui Liang (Frontiers Science Center for Transformative Molecules, Shanghai Key Laboratory for Molecular Engineering of Chiral Drugs, School of Chemistry and Chemical Engineering, Zhangjiang Institute for Advanced Study) J Jesus M. de la Fuente D Daxiang Cui