Cardiomyocyte OTUD1 drives diabetic cardiomyopathy via directly deubiquitinating AMPKα2 and inducing mitochondrial dysfunction

X Xue Han (State Key Laboratory of Advanced Chemical Power Sources, Frontiers Science Center for New Organic Matter, Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), Academy for Advanced Interdisciplinary Studies, College of Chemistry) R Ruyi Zheng (Xi’an Jiaotong University , , , ,) J Jiajia Zhang (Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion Materials, Key Laboratory of Cluster Science, Ministry of Education, Frontiers Science Center for High Energy Material, Advanced Technology Research Institute (Jinan), School of Chemistry and Chemical Engineering) Y Yanan Liu Z Ze Li G Guoxuan Liu J Jianing Zheng W Weiqi Li Z Zijun Liang M Mengyang Wang J Jie Yu Q Qiaojuan Shi H Huazhong Ying G Guang Liang

Article Details

Volume / Issue Vol. 16, Issue 1
Published July 19, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (14)

X

Xue Han

State Key Laboratory of Advanced Chemical Power Sources, Frontiers Science Center for New Organic Matter, Key Laboratory of Advanced Energy Materials Chemistry (Ministry of Education), Academy for Advanced Interdisciplinary Studies, College of Chemistry

R

Ruyi Zheng

Xi’an Jiaotong University , , , ,

J

Jiajia Zhang

Beijing Key Laboratory of Photoelectronic/Electrophotonic Conversion Materials, Key Laboratory of Cluster Science, Ministry of Education, Frontiers Science Center for High Energy Material, Advanced Technology Research Institute (Jinan), School of Chemistry and Chemical Engineering

Y

Yanan Liu

Z

Ze Li

G

Guoxuan Liu

J

Jianing Zheng

W

Weiqi Li

Z

Zijun Liang

M

Mengyang Wang

J

Jie Yu

Q

Qiaojuan Shi

H

Huazhong Ying

G

Guang Liang