Butyrophilin 2A2 promotes T cell immunoregulation via CD45 phosphatase activation and protects against murine autoimmune glomerulonephritis and pregnancy loss

Shafat Ali; Anders H. Berg; Michifumi Yamashita; Ambart E. Covarrubias; Jordan Mundell; Pranali N. Shah; Ruan Zhang; Vincent Dupont; Bong-Ha Shin; Shen Yang; Madhusudhanarao Katiki; Ramachandran Murali; Margareta D. Pisarska; Ravi Thadhani; Peter S. Heeger; Stanley C. Jordan; S. Ananth Karumanchi

doi:10.1038/s41467-025-68077-6

Butyrophilin 2A2 promotes T cell immunoregulation via CD45 phosphatase activation and protects against murine autoimmune glomerulonephritis and pregnancy loss

S Shafat Ali A Anders H. Berg M Michifumi Yamashita A Ambart E. Covarrubias J Jordan Mundell P Pranali N. Shah R Ruan Zhang (National Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University) V Vincent Dupont B Bong-Ha Shin S Shen Yang M Madhusudhanarao Katiki R Ramachandran Murali M Margareta D. Pisarska R Ravi Thadhani P Peter S. Heeger S Stanley C. Jordan S S. Ananth Karumanchi

Download PDF View Original

APA MLA Chicago BibTeX RIS

Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published January 08, 2026

DOI 10.1038/s41467-025-68077-6

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (17)

S

Shafat Ali

A

Anders H. Berg

M

Michifumi Yamashita

A

Ambart E. Covarrubias

J

Jordan Mundell

P

Pranali N. Shah

R

Ruan Zhang

National Key Laboratory of Advanced Micro and Nano Manufacture Technology, Shanghai Jiao Tong University

V

Vincent Dupont

B

Bong-Ha Shin

S

Shen Yang

M

Madhusudhanarao Katiki

R

Ramachandran Murali

M

Margareta D. Pisarska

R

Ravi Thadhani

P

Peter S. Heeger

S

Stanley C. Jordan

S

S. Ananth Karumanchi

Butyrophilin 2A2 promotes T cell immunoregulation via CD45 phosphatase activation and protects against murine autoimmune glomerulonephritis and pregnancy loss

Article Details

Journal Info

Authors (17)

Related Articles from this Journal

Synthesis of adaptive 15N-nitrosyl-Co7 nanocluster for electrocatalytic C–H functionalization

Pan-Ebolavirus nanoparticle vaccine provides protection in rodents from lethal infection by Zaire and Sudan viruses

Multi-population GWAS meta-analysis identifies bladder cancer susceptibility loci and highlights genetic regulation of smoking-related risk

Genome-wide annotation of human multi-nucleotide variants reveals widespread functional differences from single nucleotide variants

Allele-specific chromatin architecture shapes imprinted domains and coordinates a distal enhancer and antisense transcription at the mouse Mest-Copg2 domain