Bridge helix of Cas12a is an allosteric regulator of R-loop formation and RuvC activation

C Chhandosee Ganguly S Swarmistha Devi Aribam A Alberto Monteiro dos Santos L Lindsie Martin L Leonard M. Thomas Y Yihan Shao (Department of Chemistry) R Rakhi Rajan

Article Details

Volume / Issue Vol. 17, Issue 1
Published January 28, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (7)

C

Chhandosee Ganguly

S

Swarmistha Devi Aribam

A

Alberto Monteiro dos Santos

L

Lindsie Martin

L

Leonard M. Thomas

Y

Yihan Shao

Department of Chemistry

R

Rakhi Rajan