Biosynthesis of Unnatural Cyclodipeptides through Genetic Code Expansion and Cyclodipeptide Synthase Evolution

Y Yu Hu L Linqi Cheng (Department of Chemistry, Rice University, 6100 Main Street, Houston, Texas 77005, United States) Y Yijie Liu (Department of Chemistry, Rice University, 6100 Main Street, Houston, Texas 77005, United States) R Rui Liu S Shiyu Jason Jiang (Department of Chemistry, Rice University, 6100 Main Street, Houston, Texas 77005, United States) T Teng Yuan (Department of Chemistry, Rice University, 6100 Main Street, Houston, Texas 77005, United States) Y Yixian Wang (School of Chemical Engineering & Technology, Key Laboratory for Green Chemical Technology of Ministry of Education) H Haoxin Ye (Department of Chemistry, Rice University, 6100 Main Street, Houston, Texas 77005, United States) H Han Xiao (Department of Chemistry, Rice University, 6100 Main Street, Houston, Texas 77005, United States)

Article Details

Volume / Issue Vol. 147, Issue 38
Published September 24, 2025
Pages 34517-34526
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (9)

Y

Yu Hu

L

Linqi Cheng

Department of Chemistry, Rice University, 6100 Main Street, Houston, Texas 77005, United States

Y

Yijie Liu

Department of Chemistry, Rice University, 6100 Main Street, Houston, Texas 77005, United States

R

Rui Liu

S

Shiyu Jason Jiang

Department of Chemistry, Rice University, 6100 Main Street, Houston, Texas 77005, United States

T

Teng Yuan

Department of Chemistry, Rice University, 6100 Main Street, Houston, Texas 77005, United States

Y

Yixian Wang

School of Chemical Engineering & Technology, Key Laboratory for Green Chemical Technology of Ministry of Education

H

Haoxin Ye

Department of Chemistry, Rice University, 6100 Main Street, Houston, Texas 77005, United States

H

Han Xiao

Department of Chemistry, Rice University, 6100 Main Street, Houston, Texas 77005, United States