Biomineralized Engineered Bacterial Outer Membrane Vesicles as cGAS-STING Nanoagonists Synergize with Lactate Metabolism Modulation to Potentiate Immunotherapy

Q Qian-Ru Li (Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Department of Cardiology, Zhongnan Hospital) X Xiaoyang Zhang C Cheng Zhang Y Yun Zhang M Mei-Ting Niu (Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Department of Cardiology, Zhongnan Hospital) Z Zhu Chen (Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Department of Cardiology, Zhongnan Hospital) S Shi-Man Zhang (Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Department of Cardiology, Zhongnan Hospital) J Jinlian He (Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Department of Cardiology, Zhongnan Hospital) W Wei-Hai Chen (Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Department of Cardiology, Zhongnan Hospital) X Xian-Zheng Zhang (Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry)

Article Details

Volume / Issue Vol. 147, Issue 28
Published July 16, 2025
Pages 24555-24572
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (10)

Q

Qian-Ru Li

Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Department of Cardiology, Zhongnan Hospital

X

Xiaoyang Zhang

C

Cheng Zhang

Y

Yun Zhang

M

Mei-Ting Niu

Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Department of Cardiology, Zhongnan Hospital

Z

Zhu Chen

Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Department of Cardiology, Zhongnan Hospital

S

Shi-Man Zhang

Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Department of Cardiology, Zhongnan Hospital

J

Jinlian He

Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Department of Cardiology, Zhongnan Hospital

W

Wei-Hai Chen

Key Laboratory of Biomedical Polymers of Ministry of Education, Department of Chemistry, Department of Cardiology, Zhongnan Hospital

X

Xian-Zheng Zhang

Key Laboratory of Biomedical Polymers of Ministry of Education & Department of Chemistry