Journal of the American Chemical Society

Beyond Thiol-Enzyme Inhibition: Sterically Bulky NHC-Au(I) Complexes are Catalytically Active Anticancer Agents with Reprogrammed Immunomodulatory Function

Z Zhi Zhong (State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences) H Haitao Liu (State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences) Q Qiong Wu (State Key Laboratory of Magnetic Resonance Spectroscopy and Imaging, National Center for Magnetic Resonance in Wuhan, Wuhan National Laboratory for Optoelectronics, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology) B Bei Cao (College of Education Sciences) Y Yujiao Peng (State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences) M Moyi Liu (State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences) L Liang-Mei Yang (Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences) Y Yue Lin K Ke-Bin Huang (Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences) X Xiaolin Xiong (State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences) J Jinsai Shang (School of Basic Medical Sciences, State Key Laboratory of Respiratory Disease, Guangzhou National Laboratory) T Taotao Zou (State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences)
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Article Details

Volume / Issue Vol. 148, Issue 8
Published March 04, 2026
Pages 8511-8523
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society
ISSN: 0002-7863 Physical Sciences

Authors (12)

Z

Zhi Zhong

State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences

H

Haitao Liu

State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences

Q

Qiong Wu

State Key Laboratory of Magnetic Resonance Spectroscopy and Imaging, National Center for Magnetic Resonance in Wuhan, Wuhan National Laboratory for Optoelectronics, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology

B

Bei Cao

College of Education Sciences

Y

Yujiao Peng

State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences

M

Moyi Liu

State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences

L

Liang-Mei Yang

Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences

Y

Yue Lin

K

Ke-Bin Huang

Key Laboratory for Chemistry and Molecular Engineering of Medicinal Resources (Ministry of Education of China), Guangxi Key Laboratory of Chemistry and Molecular Engineering of Medicinal Resources, School of Chemistry and Pharmaceutical Sciences

X

Xiaolin Xiong

State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences

J

Jinsai Shang

School of Basic Medical Sciences, State Key Laboratory of Respiratory Disease, Guangzhou National Laboratory

T

Taotao Zou

State Key Laboratory of Anti-Infective Drug Discovery and Development, Guangdong Key Laboratory of Chiral Molecule and Drug Discovery, and School of Pharmaceutical Sciences

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