Journal of the American Chemical Society

Beyond the Amyloid Core: Modulation of Aggregate Conformational Diversity by Mutations in the Noncore Regions

M Mingrui Chen (State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biophysics and Structural Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College) Z Zhongyi Jian (State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biophysics and Structural Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College) M Mingzhan Wang (Center of Super-Diamond and Advanced Films (COSDAF), Department of Materials Science and Engineering) Z Zhenlin Liu (Department of Medical Engineering) Y Yanlian Yang (CAS Key Laboratory of Biological Effects of Nanomaterials and Nanosafety, CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology) C Chen Wang L Lanlan Yu (State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biophysics and Structural Biology) W Wenbo Zhang (Department of Materials Science and Engineering) C Chenxuan Wang (State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biophysics and Structural Biology)
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Article Details

Volume / Issue Vol. 147, Issue 37
Published September 17, 2025
Pages 33507-33517
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society
ISSN: 0002-7863 Physical Sciences

Authors (9)

M

Mingrui Chen

State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biophysics and Structural Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College

Z

Zhongyi Jian

State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biophysics and Structural Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences, School of Basic Medicine Peking Union Medical College

M

Mingzhan Wang

Center of Super-Diamond and Advanced Films (COSDAF), Department of Materials Science and Engineering

Z

Zhenlin Liu

Department of Medical Engineering

Y

Yanlian Yang

CAS Key Laboratory of Biological Effects of Nanomaterials and Nanosafety, CAS Key Laboratory of Standardization and Measurement for Nanotechnology, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology

C

Chen Wang

L

Lanlan Yu

State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biophysics and Structural Biology

W

Wenbo Zhang

Department of Materials Science and Engineering

C

Chenxuan Wang

State Key Laboratory of Common Mechanism Research for Major Diseases, Department of Biophysics and Structural Biology

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