Beyond Statistical Significance: Methodological Fragility and Censoring Bias in the 5-Year Update of CheckMate 743

C Carmen Belli (Carmen Belli, MD, PhD, Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Steven G. Gray, PhD, Thoracic Oncology Research Group, Trinity St James's Cancer Institute, St James's Hospital, Dublin, Ireland; Francesco Masedu, PhD, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy; and Luciano Mutti, MD, PhD, UniCamillus-Saint Camillus International University of Health Sciences, Rome, Italy, Italian Group for Mesothelioma and Environmental Oncology (G.I.Me.), Voghera (PV), Italy) S Steven G. Gray (Carmen Belli, MD, PhD, Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Steven G. Gray, PhD, Thoracic Oncology Research Group, Trinity St James's Cancer Institute, St James's Hospital, Dublin, Ireland; Francesco Masedu, PhD, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy; and Luciano Mutti, MD, PhD, UniCamillus-Saint Camillus International University of Health Sciences, Rome, Italy, Italian Group for Mesothelioma and Environmental Oncology (G.I.Me.), Voghera (PV), Italy) F Francesco Masedu L Luciano Mutti (Carmen Belli, MD, PhD, Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Steven G. Gray, PhD, Thoracic Oncology Research Group, Trinity St James's Cancer Institute, St James's Hospital, Dublin, Ireland; Francesco Masedu, PhD, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy; and Luciano Mutti, MD, PhD, UniCamillus-Saint Camillus International University of Health Sciences, Rome, Italy, Italian Group for Mesothelioma and Environmental Oncology (G.I.Me.), Voghera (PV), Italy)

Article Details

Volume / Issue Vol. 1, Issue 1
Published July 10, 2026
ISSN 0732-183X
Publisher Lippincott Williams & Wilkins

Journal Info

Journal of Clinical Oncology

Lippincott Williams & Wilkins

ISSN: 0732-183X Health Sciences

Authors (4)

C

Carmen Belli

Carmen Belli, MD, PhD, Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Steven G. Gray, PhD, Thoracic Oncology Research Group, Trinity St James's Cancer Institute, St James's Hospital, Dublin, Ireland; Francesco Masedu, PhD, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy; and Luciano Mutti, MD, PhD, UniCamillus-Saint Camillus International University of Health Sciences, Rome, Italy, Italian Group for Mesothelioma and Environmental Oncology (G.I.Me.), Voghera (PV), Italy

S

Steven G. Gray

Carmen Belli, MD, PhD, Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Steven G. Gray, PhD, Thoracic Oncology Research Group, Trinity St James's Cancer Institute, St James's Hospital, Dublin, Ireland; Francesco Masedu, PhD, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy; and Luciano Mutti, MD, PhD, UniCamillus-Saint Camillus International University of Health Sciences, Rome, Italy, Italian Group for Mesothelioma and Environmental Oncology (G.I.Me.), Voghera (PV), Italy

F

Francesco Masedu

L

Luciano Mutti

Carmen Belli, MD, PhD, Division of New Drugs and Early Drug Development for Innovative Therapies, European Institute of Oncology, IRCCS, Milan, Italy; Steven G. Gray, PhD, Thoracic Oncology Research Group, Trinity St James's Cancer Institute, St James's Hospital, Dublin, Ireland; Francesco Masedu, PhD, Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy; and Luciano Mutti, MD, PhD, UniCamillus-Saint Camillus International University of Health Sciences, Rome, Italy, Italian Group for Mesothelioma and Environmental Oncology (G.I.Me.), Voghera (PV), Italy