Beyond static measurements: dynamic frailty improves survival prediction in multiple myeloma
Abstract
Abstract The level of frailty, according to the International Myeloma Working Group frailty index, is highly dynamic during antimyeloma treatment. Dynamic frailty assessment improved the prediction of survival and early mortality compared with the prognostic value of static frailty level at baseline.
Article Details
Authors (25)
Febe Smits
6Department of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
Kaz Groen
1Department of Hematology, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
Mark-David Levin
Albert Schweitzer Ziekenhuis, Dordrecht, the Netherlands
Claudia A. M. Stege
5Department of Hematology, Erasmus MC, University Medical Center, Rotterdam, The Netherlands
Roel van Kampen
6Department of Internal Medicine, Zuyderland Hospital, Sittard, The Netherlands
Ellen van der Spek
10Rijnstate Hospital, Arnhem, Netherlands
Yavuz M. Bilgin
8Department of Internal Medicine, Ardz Hospital, Goes, The Netherlands
Noortje Thielen
9Department of Internal Medicine, Diakonessenhuis, Utrecht, The Netherlands
Inger Nijhof
3St. Antonius Ziekenhuis, Nieuwegein, Netherlands
Inge Ludwig
9Bernhoven Hospital, Uden, Netherlands
Esther G. M. de Waal
12Department of Internal Medicine, Medical Center Leeuwarden, Leeuwarden, The Netherlands
Yorick Sandberg
Maasstad Hospital
Alain Kentos
Department of Hematology, Hôpital de Jolimont, Haine-Saint-Paul, Belgium
Gert-Jan Timmers
15Department of Internal Medicine, Amstelland Hospital, Amstelveen, The Netherlands
Josien C. Regelink
16Department of Internal Medicine, Meander Medical Center, Amersfoort, The Netherlands
Matthijs Westerman
17Department of Internal Medicine, Northwest Clinics, Alkmaar, The Netherlands
Koen de Heer
24Department of Internal Medicine, Flevoziekenhuis, Almere, The Netherlands
Marie-Christiane Vekemans
23Department of Hematology, Cliniques Universitaires Saint-Luc, Brussels, Belgium
Nazik Durdu-Rayman
20Department of Internal Medicine, Franciscus Hospital, Schiedam, The Netherlands
Nicole C. H. P. de Graauw
21Department of Internal Medicine, Bravis Hospital, Roosendaal, The Netherlands
Maarten R. Seefat
1Department of Hematology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, The Netherlands
Niels W. C. J. van de Donk
Paula F. Ypma
3Department of Hematology, Haga Hospital, The Hague, The Netherlands
Kazem Nasserinejad
3ErasmusMC, Rotterdam, Netherlands
Sonja Zweegman