Bayesian inference of a spatially dependent semi-Markovian model with application to Madagascar Covid’19 data

A Angelo Raherinirina S Stefana Tabera Tsilefa T Tsidikaina Nirilanto S Solym M. Manou-Abi

Abstract

This article presents an approach to stochastic analysis of disease dynamics. We develop an explicit semi-Markovian model that accounts for spatial dependence, operating in discrete time over a finite state space. The model allowed us to have a propagation model conditioned by neighboring states and quantifies two key characteristics : spatial propagation timescales and propagation law in a region dependent on neighboring states. The model is inferred from data collected on the spread of Covid’19 in Madagascar’s 22 regions, using the Bayesian approach to get a better idea of model parameter values. The result has demonstrated the effect of neighborhoods on the propagation dynamics of diseases. We conclude with a discussion of potential future theoretical developments.

Article Details

Journal PLoS ONE
Volume / Issue Vol. 20, Issue 7
Published July 07, 2025
Pages e0326264
ISSN 1932-6203
Publisher Public Library of Science

Journal Info

PLoS ONE

Public Library of Science

ISSN: 1932-6203 Open Access Health Sciences

Authors (4)

A

Angelo Raherinirina

S

Stefana Tabera Tsilefa

T

Tsidikaina Nirilanto

S

Solym M. Manou-Abi