Autologous HIV-specific T cell therapy targeting conserved epitopes is well-tolerated in six adults with HIV: an open-label, single-arm phase 1 study

Danielle K. Sohai; Michael D. Keller; Patrick J. Hanley; Fahmida Hoq; Divyesh Kukadiya; Anushree Datar; Emily Reynolds; Dennis C. Copertino; Christopher Lazarski; Chase D. McCann; Jay Tanna; Abeer Shibli; Haili Lang; Anqing Zhang; Pamela A. Chansky; Cecilia Motta; Tan T. Huynh; Bridget Dwyer; Andrew Wilson; Rebecca Lynch; Talia M. Mota; Winiffer D. Conce Alberto; Zabrina L. Brumme; Natalie N. Kinloch; Conrad Russell Y. Cruz; Lynsay MacLaren Ehui; Sarah Henn; R. Brad Jones; Catherine M. Bollard

doi:10.1038/s41467-025-59810-2

Autologous HIV-specific T cell therapy targeting conserved epitopes is well-tolerated in six adults with HIV: an open-label, single-arm phase 1 study

D Danielle K. Sohai M Michael D. Keller P Patrick J. Hanley F Fahmida Hoq D Divyesh Kukadiya A Anushree Datar E Emily Reynolds D Dennis C. Copertino C Christopher Lazarski C Chase D. McCann J Jay Tanna A Abeer Shibli H Haili Lang A Anqing Zhang P Pamela A. Chansky C Cecilia Motta T Tan T. Huynh B Bridget Dwyer A Andrew Wilson R Rebecca Lynch T Talia M. Mota W Winiffer D. Conce Alberto Z Zabrina L. Brumme N Natalie N. Kinloch C Conrad Russell Y. Cruz L Lynsay MacLaren Ehui S Sarah Henn R R. Brad Jones C Catherine M. Bollard (Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine)

Download PDF View Original

APA MLA Chicago BibTeX RIS

Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published May 15, 2025

DOI 10.1038/s41467-025-59810-2

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (29)

D

Danielle K. Sohai

M

Michael D. Keller

P

Patrick J. Hanley

F

Fahmida Hoq

D

Divyesh Kukadiya

A

Anushree Datar

E

Emily Reynolds

D

Dennis C. Copertino

C

Christopher Lazarski

C

Chase D. McCann

J

Jay Tanna

A

Abeer Shibli

H

Haili Lang

A

Anqing Zhang

P

Pamela A. Chansky

C

Cecilia Motta

T

Tan T. Huynh

B

Bridget Dwyer

A

Andrew Wilson

R

Rebecca Lynch

T

Talia M. Mota

W

Winiffer D. Conce Alberto

Z

Zabrina L. Brumme

N

Natalie N. Kinloch

C

Conrad Russell Y. Cruz

L

Lynsay MacLaren Ehui

S

Sarah Henn

R

R. Brad Jones

C

Catherine M. Bollard

Department of Oncology, Sidney Kimmel Comprehensive Cancer Center, Johns Hopkins University School of Medicine

Autologous HIV-specific T cell therapy targeting conserved epitopes is well-tolerated in six adults with HIV: an open-label, single-arm phase 1 study

Article Details

Journal Info

Authors (29)

Related Articles from this Journal

Synthesis of adaptive 15N-nitrosyl-Co7 nanocluster for electrocatalytic C–H functionalization

Pan-Ebolavirus nanoparticle vaccine provides protection in rodents from lethal infection by Zaire and Sudan viruses

Multi-population GWAS meta-analysis identifies bladder cancer susceptibility loci and highlights genetic regulation of smoking-related risk

Genome-wide annotation of human multi-nucleotide variants reveals widespread functional differences from single nucleotide variants

Allele-specific chromatin architecture shapes imprinted domains and coordinates a distal enhancer and antisense transcription at the mouse Mest-Copg2 domain