Atom-specific vibrational analysis reveals labile bonds in linear and branched PFOA molecules

J Jesús N. Pedroza-Montero (Department of Physics, Central Michigan University 1 , Mt Pleasant, Michigan 48859,) K Kushantha P. K. Withanage (Department of Physics, University of Texas at El Paso 2 , El Paso, Texas 79968,) A Anri Karanovich (Department of Physics, Central Michigan University 1 , Mt Pleasant, Michigan 48859,) P Pardeep Kaur (Department of Physics, University of Texas at El Paso 2 , El Paso, Texas 79968,) Y Yoh Yamamoto (Department of Physics, University of Texas at El Paso 2 , El Paso, Texas 79968,) S Sonam C. Lhamo (Department of Physics, University of Texas at El Paso 2 , El Paso, Texas 79968,) J Jenna A. Bilbrey (Physical Detection Systems and Deployment Division, Pacific Northwest National Laboratory 3 , Richland, Washington 99352,) E Eric J. Bylaska (Physical Sciences Division, Pacific Northwest National Laboratory 4 , Richland, Washington 99354,) K Karol Kowalski (Pacific Northwest National Laboratory, Physical Sciences Division 1 , Richland, Washington 99354,) T Tunna Baruah (Department of Physics, University of Texas at El Paso 2 , El Paso, Texas 79968,) M Mark R. Pederson (Department of Physics, University of Texas at El Paso 2 , El Paso, Texas 79968,) K Koblar A. Jackson (Department of Physics and Science of Advanced Materials Program)

Abstract

We have performed atom-specific vibrational analyses of a large number of perfluorooctanoic acid isomers as well as their anions and show that differences in the vibrational features of corresponding anion and neutral molecules clearly identify the C–F bonds that are most strongly activated in the anions. We discuss two analysis tools for associating vibrational modes with individual atoms, both based on density functional theory calculations. The first involves computing the Einstein frequencies for a given atom and the second projects the full vibrational spectrum onto a given atom using participation factors derived from the normal mode eigenvectors. We show that the two methods give results that are qualitatively the same and that either can be used to identify the most labile C–F bonds in the anions. We also show that the results of the vibrational analyses are consistent with systematically computed F atom removal energies. The vibrational analysis tools are shown to be related to the local mode analysis of Cremer and co-workers. Finally, we compare and contrast branched and linear PFAS molecules and analogous hydrogenated carbon chains.

Article Details

Volume / Issue Vol. 164, Issue 14
Published April 14, 2026
ISSN 0021-9606
Publisher American Institute of Physics

Journal Info

The Journal of Chemical Physics

American Institute of Physics

ISSN: 0021-9606 Physical Sciences

Authors (12)

J

Jesús N. Pedroza-Montero

Department of Physics, Central Michigan University 1 , Mt Pleasant, Michigan 48859,

K

Kushantha P. K. Withanage

Department of Physics, University of Texas at El Paso 2 , El Paso, Texas 79968,

A

Anri Karanovich

Department of Physics, Central Michigan University 1 , Mt Pleasant, Michigan 48859,

P

Pardeep Kaur

Department of Physics, University of Texas at El Paso 2 , El Paso, Texas 79968,

Y

Yoh Yamamoto

Department of Physics, University of Texas at El Paso 2 , El Paso, Texas 79968,

S

Sonam C. Lhamo

Department of Physics, University of Texas at El Paso 2 , El Paso, Texas 79968,

J

Jenna A. Bilbrey

Physical Detection Systems and Deployment Division, Pacific Northwest National Laboratory 3 , Richland, Washington 99352,

E

Eric J. Bylaska

Physical Sciences Division, Pacific Northwest National Laboratory 4 , Richland, Washington 99354,

K

Karol Kowalski

Pacific Northwest National Laboratory, Physical Sciences Division 1 , Richland, Washington 99354,

T

Tunna Baruah

Department of Physics, University of Texas at El Paso 2 , El Paso, Texas 79968,

M

Mark R. Pederson

Department of Physics, University of Texas at El Paso 2 , El Paso, Texas 79968,

K

Koblar A. Jackson

Department of Physics and Science of Advanced Materials Program