ARID1A loss drives gastric signet ring cell carcinoma by regulating mucin production and secretion

H Hongyu Liu (School of Materials and Energy) A Ailing Zhong Z Zhenghao Lu (Chengdu OrganoidMed Medical Laboratory, West China Health Valley) L Limin Gao M Mengsha Zhang J Jiaxin Li Y Yingjie Wang Y Yiyun Wang (State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University) L Lanxin Zhang (State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University) J Jiabo Zhang X Xiangyu Pan (Key Laboratory of Green Printing, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China) X Xuelan Chen (State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University) J Jingyao Chen (State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University) S Siyu He X Xinyuan Wang X Xudong Wan X Xintong Deng (State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University) T Tingfa Peng J Jian Wang J Jiajia Du K Kun Yang K Kai Liu X Xinzu Chen X Xiaolong Chen (Beijing National Laboratory for Condensed Matter Physics) Z Zhe Feng B Baohong Wu (State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University) J Jing Xu L Linyong Zhao W Weihan Zhang (Beijing Key Laboratory of Optoelectronic Functional Materials & Micro-Nano Devices, School of Physics) S Shengyong Yang Y Yuan Wang L Lu Chen Z Zhihong Xue C Chengjian Zhao (State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University) L Lunzhi Dai F Feifei Na (Department of Thoracic Oncology, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University) J Jiankun Hu Y Yu Liu C Chong Chen (Department of Thoracic Oncology, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University)

Article Details

Volume / Issue Vol. 17, Issue 1
Published June 02, 2026
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (39)

H

Hongyu Liu

School of Materials and Energy

A

Ailing Zhong

Z

Zhenghao Lu

Chengdu OrganoidMed Medical Laboratory, West China Health Valley

L

Limin Gao

M

Mengsha Zhang

J

Jiaxin Li

Y

Yingjie Wang

Y

Yiyun Wang

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University

L

Lanxin Zhang

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University

J

Jiabo Zhang

X

Xiangyu Pan

Key Laboratory of Green Printing, CAS Research/Education Center for Excellence in Molecular Sciences, Institute of Chemistry, Chinese Academy of Sciences, Beijing 100190, P. R. China

X

Xuelan Chen

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University

J

Jingyao Chen

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University

S

Siyu He

X

Xinyuan Wang

X

Xudong Wan

X

Xintong Deng

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University

T

Tingfa Peng

J

Jian Wang

J

Jiajia Du

K

Kun Yang

K

Kai Liu

X

Xinzu Chen

X

Xiaolong Chen

Beijing National Laboratory for Condensed Matter Physics

Z

Zhe Feng

B

Baohong Wu

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University

J

Jing Xu

L

Linyong Zhao

W

Weihan Zhang

Beijing Key Laboratory of Optoelectronic Functional Materials & Micro-Nano Devices, School of Physics

S

Shengyong Yang

Y

Yuan Wang

L

Lu Chen

Z

Zhihong Xue

C

Chengjian Zhao

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University

L

Lunzhi Dai

F

Feifei Na

Department of Thoracic Oncology, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University

J

Jiankun Hu

Y

Yu Liu

C

Chong Chen

Department of Thoracic Oncology, State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University