Apoptosis-targeting BH3 mimetics: transforming treatment for patients with acute myeloid leukaemia

Antonino Glaviano; Ellen Weisberg; Hiu Y. Lam; Donavan J. J. Tan; Andrew J. Innes; Yubin Ge; Catherine E. Lai; Wendy Stock; Christina Glytsou; Linda Smit; Tatsushi Yoshida; Tian Y. Zhang; Vanessa E. Kennedy; B. Douglas Smith; Thomas Mercher; Stéphane de Botton; Patrizia Diana; Marina Konopleva; Michael J. Mauro; James D. Griffin; Courtney D. DiNardo; Alan P. Kumar

doi:10.1038/s41571-025-01068-0

Apoptosis-targeting BH3 mimetics: transforming treatment for patients with acute myeloid leukaemia

A Antonino Glaviano E Ellen Weisberg H Hiu Y. Lam D Donavan J. J. Tan A Andrew J. Innes Y Yubin Ge C Catherine E. Lai W Wendy Stock C Christina Glytsou L Linda Smit T Tatsushi Yoshida T Tian Y. Zhang V Vanessa E. Kennedy B B. Douglas Smith T Thomas Mercher S Stéphane de Botton P Patrizia Diana M Marina Konopleva M Michael J. Mauro J James D. Griffin C Courtney D. DiNardo (Department of Leukemia The University of Texas MD Anderson Cancer Center Houston Texas USA) A Alan P. Kumar

Download PDF View Original

APA MLA Chicago BibTeX RIS

Article Details

Journal Nature Reviews Clinical Oncology

Volume / Issue Vol. 22, Issue 11

Published November 01, 2025

Pages 847-868

DOI 10.1038/s41571-025-01068-0

ISSN 1759-4774

Publisher Springer Science and Business Media LLC

Journal Info

Nature Reviews Clinical Oncology

Springer Science and Business Media LLC

ISSN: 1759-4774 Q1 Medicine

Authors (22)

A

Antonino Glaviano

E

Ellen Weisberg

H

Hiu Y. Lam

D

Donavan J. J. Tan

A

Andrew J. Innes

Y

Yubin Ge

C

Catherine E. Lai

W

Wendy Stock

C

Christina Glytsou

L

Linda Smit

T

Tatsushi Yoshida

T

Tian Y. Zhang

V

Vanessa E. Kennedy

B

B. Douglas Smith

T

Thomas Mercher

S

Stéphane de Botton

P

Patrizia Diana

M

Marina Konopleva

M

Michael J. Mauro

J

James D. Griffin

C

Courtney D. DiNardo

Department of Leukemia The University of Texas MD Anderson Cancer Center Houston Texas USA

A

Alan P. Kumar

Apoptosis-targeting BH3 mimetics: transforming treatment for patients with acute myeloid leukaemia

Article Details

Journal Info

Authors (22)

Related Articles from this Journal

Ibrutinib improves overall survival in patients with mantle cell lymphoma

First-line zanidatamab–chemotherapy with or without tislelizumab improves survival in advanced-stage HER2+ GEA

Clinical implementation of multi-cancer early detection tests: can we find a path forward?

Pan-RAS inhibitor daraxonrasib shows promise in pancreatic cancer

Liquid biopsy to inform adjuvant decisions during neoadjuvant chemotherapy — a full-circle moment for nasopharyngeal cancer