Antisense oligonucleotides to KIF1A polymorphisms expand targets and rescue patient-derived neurons in vitro

Michael V. Zuccaro; Randee E. Young; Jiangyuan Hu; Patricia Lanzano; Ekaterina Semenova; Xiaoqi Lin; Alicja Skowronski; Yufeng Shen; Tae Hyun Kim; Danny E. Miller; Noelle Germain; Patrick Sarmiere; Charles A. LeDuc; Wendy K. Chung

doi:10.1038/s41467-025-67752-y

Antisense oligonucleotides to KIF1A polymorphisms expand targets and rescue patient-derived neurons in vitro

M Michael V. Zuccaro R Randee E. Young J Jiangyuan Hu P Patricia Lanzano E Ekaterina Semenova (Waksman Institute for Microbiology, Rutgers, The State University of New Jersey) X Xiaoqi Lin A Alicja Skowronski Y Yufeng Shen (Department of Systems Biology, Columbia University Irving Medical Center) T Tae Hyun Kim D Danny E. Miller N Noelle Germain P Patrick Sarmiere C Charles A. LeDuc W Wendy K. Chung (Department of Pediatrics, Boston Children’s Hospital, Harvard Medical School)

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Article Details

Journal Nature Communications

Volume / Issue Vol. 17, Issue 1

Published January 09, 2026

DOI 10.1038/s41467-025-67752-y

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (14)

M

Michael V. Zuccaro

R

Randee E. Young

J

Jiangyuan Hu

P

Patricia Lanzano

E

Ekaterina Semenova

Waksman Institute for Microbiology, Rutgers, The State University of New Jersey

X

Xiaoqi Lin

A

Alicja Skowronski

Y

Yufeng Shen

Department of Systems Biology, Columbia University Irving Medical Center

T

Tae Hyun Kim

D

Danny E. Miller

N

Noelle Germain

P

Patrick Sarmiere

C

Charles A. LeDuc

W

Wendy K. Chung

Department of Pediatrics, Boston Children’s Hospital, Harvard Medical School

Antisense oligonucleotides to KIF1A polymorphisms expand targets and rescue patient-derived neurons in vitro

Article Details

Journal Info

Authors (14)

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