Analysis of human factor H-related gene and protein expressed in rheumatoid arthritis synovium identifies a novel mechanism promoting dysregulated complement pathway activation

D Dmitri Simberg R Robert I. Scheinman R Rachel M. Frank J Jennifer Anolik D Darren Tabechian R Ralf Thiele J Jennifer Hossler B Brendan Boyce N Nida Meednu J Javier Rangel-Moreno C Christopher Ritchlin V Vivian Bykerk L Laura Donlin S Susan Goodman E Ed DiCarlo D Dana Orange J John Carrino N Nwawka Endo Yoshimi R Rahul Satija L Lionel Ivashkiv A Alessandra Pernis R Robert Darnell M Mark Figgie M Michael McNamara. Mandy J. McGeachy J Jay Kolls A Aaron Wise A Andrew Cordle, Peter Gregersen Dian Horowitz A Andrew D. Filer J Jason Turner Holly Adams S Stephen Kelly Rebecca Hands K Kevin Wei D Deepak Rao F Fumitaka Mizoguchi K Kevin D. Deane J Jennifer A. Seifert N Nirmal K. Banda L Larry W. Moreland A Alexander Merkle C Colin Strickland G Gary S. Firestein D David Boyle M Michael H. Weisman A Ami Ben-Artzi L Lindsy Forbess E Ellen Gravallese K Karen Salomon-Escoto H Harris Perlman A Arthur Mandelin Emily Bacalao D Deborah Parks J John Atkinson J Joan Bathon E Eric Matteson R Rachel Lau C Costantino Pitzalis M Myles J. Lewis (Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute and Barts and The London School of Medicine and Dentistry, Queen Mary University of London) V V. Michael Holers

Article Details

Volume / Issue Vol. 15, Issue 1
Published June 04, 2025
ISSN 2045-2322
Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (56)

D

Dmitri Simberg

R

Robert I. Scheinman

R

Rachel M. Frank

J

Jennifer Anolik

D

Darren Tabechian

R

Ralf Thiele

J

Jennifer Hossler

B

Brendan Boyce

N

Nida Meednu

J

Javier Rangel-Moreno

C

Christopher Ritchlin

V

Vivian Bykerk

L

Laura Donlin

S

Susan Goodman

E

Ed DiCarlo

D

Dana Orange

J

John Carrino

N

Nwawka Endo Yoshimi

R

Rahul Satija

L

Lionel Ivashkiv

A

Alessandra Pernis

R

Robert Darnell

M

Mark Figgie

M

Michael McNamara. Mandy J. McGeachy

J

Jay Kolls

A

Aaron Wise

A

Andrew Cordle, Peter Gregersen Dian Horowitz

A

Andrew D. Filer

J

Jason Turner Holly Adams

S

Stephen Kelly Rebecca Hands

K

Kevin Wei

D

Deepak Rao

F

Fumitaka Mizoguchi

K

Kevin D. Deane

J

Jennifer A. Seifert

N

Nirmal K. Banda

L

Larry W. Moreland

A

Alexander Merkle

C

Colin Strickland

G

Gary S. Firestein

D

David Boyle

M

Michael H. Weisman

A

Ami Ben-Artzi

L

Lindsy Forbess

E

Ellen Gravallese

K

Karen Salomon-Escoto

H

Harris Perlman

A

Arthur Mandelin Emily Bacalao

D

Deborah Parks

J

John Atkinson

J

Joan Bathon

E

Eric Matteson

R

Rachel Lau

C

Costantino Pitzalis

M

Myles J. Lewis

Centre for Experimental Medicine & Rheumatology, William Harvey Research Institute and Barts and The London School of Medicine and Dentistry, Queen Mary University of London

V

V. Michael Holers