An Intelligence Programmable Intrathecal Injection System Based on Tween 80‐Confined Halide Perovskite Optoelectronic Memristor
Abstract
Abstract Lead‐free inorganic perovskites have emerged as promising candidates to replace the lead‐based perovskites and expedite the commercialization of optoelectronic devices, owing to their exceptional optoelectronic properties, tunable bandgap, and long carrier diffusion lengths. However, uncontrollable nucleation and crystal growth of perovskites pose a major challenge to device performance. Herein, a Tween 80‐confined Cs 2 AgBiBr 6 ‐based optoelectronic memristor is presented that exhibits both electronic synaptic functionality (ESF) and transient photoresponse (TPR). The Tween 80 confinement strategy effectively suppresses bromine vacancy (Br vac ) and promotes the formation of a high‐quality, pinhole‐free perovskite film, which endows the device with outstanding optoelectronic performance. Leveraging the ESF under electrical stimulation, the as‐fabricated device achieves highly efficient pattern recognition. Under optical stimulation, it demonstrates a TPR with 20 ms response time, an extended durability of 931.7 s, and excellent repeatability over 1000 cycles at 5 Hz. Furthermore, the device achieves all‐optical writing and erasing through combined optical stimuli, enabling complex image encryption/writing tasks. Finally, an all‐optically controlled intrathecal injection system is designed based on the device, incorporating six specific drug release strategies. Therefore, this work provides innovative insights into the application of optoelectronic memristors in biomedical and life sciences, paving the way for the development of smart medicine.
Article Details
Authors (11)
Kaikai Gao
Frontier Institute of Science and Technology, and Interdisciplinary Research Center of Frontier Science and Technology Xi'an Jiaotong University Xi'an Shaanxi 710049 China
Zelin Cao
Key Laboratory of Molecular Biophysics of the Ministry of Education, Hubei Provincial Research Center for Basic Biological Sciences, College of Life Science and Technology, Huazhong University of Science and Technology
Bai Sun
Frontier Institute of Science and Technology Interdisciplinary Research Center of Frontier science and technology State Key Laboratory for Strength and Vibration of Mechanical Structures Engineering Research Center of Key Materials for Efficient Utilization of Clean Energy of Shaanxi Province Xi'an Key Laboratory of Electronic Devices and Material Chemistry Institute of New Concept Sensors and Molecular Materials Shaanxi Key Laboratory of New Conceptual Sensors and Molecular Materials Xi'an...
Longhui Fu
Department of Neurosurgery The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an Shaanxi 710004 China
Huangtao Chen
Department of Neurosurgery The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an Shaanxi 710004 China
Mengna Wang
State Key Laboratory of Catalysis, Dalian National Laboratory for Clean Energy, iChEM (Collaborative Innovation Center of Chemistry for Energy Materials)
Guangdong Zhou
Jian Lv
Xiaoliang Chen
State Key Laboratory of Synergistic Chem-Bio Synthesis, State Key Laboratory of Micro-Nano Engineering Science, School of Chemistry and Chemical Engineering, New Cornerstone Science Laboratory, Frontiers Science Center for Transformative Molecules, Zhang Jiang Institute for Advanced Study and National Center for Translational Medicine
Xianxia Yan
Department of Neurosurgery The Second Affiliated Hospital of Xi'an Jiaotong University Xi'an Shaanxi 710004 China
Jinyou Shao
Micro-and Nano-Technology Research Center, State Key Laboratory for Manufacturing Systems Engineering, School of Mechanical Engineering, Xi’an Jiaotong University