An evolutionary T119R substitution in the macaque T-cell immunoreceptor TIGIT enables proteolytic shedding and reveals clinical antibody vulnerabilities

E Eric Pirillo F Francis Freenor V B Brice E.N. Wamba S Sanchita Bhatnagar T Tanmoy Mondal J Jogender Tushir-Singh

Article Details

Volume / Issue Vol. 302, Issue 1
Published January 01, 2026
Pages 110962
ISSN 0021-9258
Publisher Elsevier BV

Journal Info

Journal of Biological Chemistry

Elsevier BV

ISSN: 0021-9258 Open Access Life Sciences

Authors (6)

E

Eric Pirillo

F

Francis Freenor V

B

Brice E.N. Wamba

S

Sanchita Bhatnagar

T

Tanmoy Mondal

J

Jogender Tushir-Singh