An effective brain stroke diagnosis strategy based on feature extraction and hybrid classifier

M Maha Samir Elsayed G Gehad Ahmed Saleh A Ahmed I. Saleh A Abeer Twakol Khalil

Abstract

Abstract Stroke is a leading cause of death and long-term disability worldwide, and early detection remains a significant clinical challenge. This study proposes an Effective Brain Stroke Diagnosis Strategy (EBDS). The hybrid deep learning framework integrates Vision Transformer (ViT) and VGG16 to enable accurate and interpretable stroke detection from CT images. The model was trained and evaluated using a publicly available dataset from Kaggle, achieving impressive results: a test accuracy of 99.6%, a precision of 1.00 for normal cases and 0.98 for stroke cases, a recall of 0.99 for normal cases and 1.00 for stroke cases, and an overall F1-score of 0.99. These results demonstrate the robustness and reliability of the EBDS model, which outperforms several recent state-of-the-art methods. To enhance clinical trust, the model incorporates explainability techniques, such as Grad-CAM and LIME, which provide visual insights into its decision-making process. The EBDS framework is designed for real-time application in emergency settings, offering both high diagnostic performance and interpretability. This work addresses a critical research gap in early brain stroke diagnosis and contributes a scalable, explainable, and clinically relevant solution for medical imaging diagnostics.

Article Details

Volume / Issue Vol. 15, Issue 1
Published August 14, 2025
ISSN 2045-2322
Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (4)

M

Maha Samir Elsayed

G

Gehad Ahmed Saleh

A

Ahmed I. Saleh

A

Abeer Twakol Khalil