An anti-virulence drug targeting the evolvability protein Mfd protects against infections with antimicrobial resistant ESKAPE pathogens

Seav-Ly Tran; Lucie Lebreuilly; Delphine Cormontagne; Samantha Samson; Thu Ba Tô; Marie Stosskopf; Rozenn Dervyn; Anne Grießhammer; Jacobo de la Cuesta-Zuluaga; Lisa Maier; Thierry Naas; Simona Mura; Didier Rognan; Julien Nicolas; Gwenaëlle André; Nalini Ramarao

doi:10.1038/s41467-025-58282-8

An anti-virulence drug targeting the evolvability protein Mfd protects against infections with antimicrobial resistant ESKAPE pathogens

S Seav-Ly Tran L Lucie Lebreuilly D Delphine Cormontagne S Samantha Samson T Thu Ba Tô M Marie Stosskopf R Rozenn Dervyn A Anne Grießhammer J Jacobo de la Cuesta-Zuluaga L Lisa Maier T Thierry Naas (Team RESIST, INSERM U1184, Université Paris-Saclay, Faculté de Médecine, Bacteriology ward, Hôpital de Bicêtre, 3ème étage, 78 rue du Gal Leclerc, Paris 94270, France) S Simona Mura D Didier Rognan J Julien Nicolas (Université Paris-Saclay, CNRS, Institut Galien Paris-Saclay) G Gwenaëlle André N Nalini Ramarao

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Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published April 28, 2025

DOI 10.1038/s41467-025-58282-8

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (16)

S

Seav-Ly Tran

L

Lucie Lebreuilly

D

Delphine Cormontagne

S

Samantha Samson

T

Thu Ba Tô

M

Marie Stosskopf

R

Rozenn Dervyn

A

Anne Grießhammer

J

Jacobo de la Cuesta-Zuluaga

L

Lisa Maier

T

Thierry Naas

Team RESIST, INSERM U1184, Université Paris-Saclay, Faculté de Médecine, Bacteriology ward, Hôpital de Bicêtre, 3ème étage, 78 rue du Gal Leclerc, Paris 94270, France

S

Simona Mura

D

Didier Rognan

J

Julien Nicolas

Université Paris-Saclay, CNRS, Institut Galien Paris-Saclay

G

Gwenaëlle André

N

Nalini Ramarao

An anti-virulence drug targeting the evolvability protein Mfd protects against infections with antimicrobial resistant ESKAPE pathogens

Article Details

Journal Info

Authors (16)

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