An Alternative Mechanism for C–C Desaturation Underscores a Dual-Controlled Mechanism for the Fate of Radical Intermediate in Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenase DfmD

Xuan Zhang

Lanteng Wang

State Key Laboratory of Quantitative Synthetic Biology

Jia Liu

Tzu-Yu Chen

Department of Chemistry

Shengheng Yan

State Key Laboratory of Physical Chemistry of Solid Surfaces and Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, College of Chemistry and Chemical Engineering

Wei-chen Chang

Department of Chemistry

Sason Shaik

Institute of Chemistry, The Hebrew University of Jerusalem, Edmond J. Safra Campus, Givat Ram, Jerusalem 9190401, Israel

Jiahai Zhou

School of Food Science and Pharmaceutical Engineering

Binju Wang

State Key Laboratory of Physical Chemistry of Solid Surfaces and Fujian Provincial Key Laboratory of Theoretical and Computational Chemistry, College of Chemistry and Chemical Engineering