Allosteric Inhibition of PKMYT1 Induces a Unique, Inactive ATP Binding Site Conformation

N Noah B. Herrington (Department of Pharmacological Sciences) S Susmita Khamrui (Department of Pharmacological Sciences) Y Yihan Zhao (Department of Pharmacological Sciences) C Carisse Lansiquot (Department of Pharmacological Sciences) R Ruoxi Wu (Department of Pharmacological Sciences) G Gaurav Pandey M Michael B. Lazarus (Department of Pharmacological Sciences) A Avner Schlessinger (Department of Pharmacological Sciences)

Article Details

Volume / Issue Vol. 148, Issue 23
Published June 17, 2026
Pages 24274-24286
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (8)

N

Noah B. Herrington

Department of Pharmacological Sciences

S

Susmita Khamrui

Department of Pharmacological Sciences

Y

Yihan Zhao

Department of Pharmacological Sciences

C

Carisse Lansiquot

Department of Pharmacological Sciences

R

Ruoxi Wu

Department of Pharmacological Sciences

G

Gaurav Pandey

M

Michael B. Lazarus

Department of Pharmacological Sciences

A

Avner Schlessinger

Department of Pharmacological Sciences