Alcohol Use and Cardiovascular Disease: A Scientific Statement From the American Heart Association

M Mariann R. Piano G Gregory M. Marcus (Division of Cardiology, University of California, San Francisco, San Francisco) D Dawn M. Aycock J Jennifer Buckman C Chueh-Lung Hwang S Susanna C. Larsson K Kenneth J. Mukamal M Michael Roerecke

Abstract

Alcohol is one of the most commonly consumed substances in the world, exhibiting complex relationships with multiple aspects of cardiovascular health and disease. The majority of the research on the topic is observational and therefore prone to bias and confounding. The available evidence suggests no risk to possible risk reduction when alcohol is consumed in low amounts (such as no more than 1 to 2 drinks a day) in regard to coronary artery disease, stroke, sudden death, and possibly heart failure. The risk associated with consuming 1 to 2 drinks a day on atrial fibrillation remains unknown. More randomized trials of low to moderate alcohol consumption are needed for more definitive conclusions. In stark contrast, binge drinking or consuming on average ≥3 drinks a day is consistently associated with worse outcomes in every cardiovascular disease entity studied. Considering the level of evidence, it remains unknown whether drinking is part of a healthy lifestyle and therefore clinicians should reinforce healthy lifestyle behaviors such as regularly engaging in physical activity, avoiding tobacco use, and maintaining healthy body weight.

Article Details

Journal Circulation
Volume / Issue Vol. 152, Issue 1
Published July 08, 2025
ISSN 0009-7322
Publisher Lippincott Williams & Wilkins

Journal Info

Circulation

Lippincott Williams & Wilkins

ISSN: 0009-7322 Health Sciences

Authors (8)

M

Mariann R. Piano

G

Gregory M. Marcus

Division of Cardiology, University of California, San Francisco, San Francisco

D

Dawn M. Aycock

J

Jennifer Buckman

C

Chueh-Lung Hwang

S

Susanna C. Larsson

K

Kenneth J. Mukamal

M

Michael Roerecke