Advancing medical question answering with a knowledge embedding transformer

X Xiang Zhu (Hefei National Research Center for Physical Sciences at the Microscale, CAS Center for Excellence in Quantum Information and Quantum Physics, and New Cornerstone Science Laboratory) M Mustaqeem Khan A Abdelmalik Taleb-Ahmed A Alice Othmani

Abstract

Efficient medical question answering is essential for better patient care. Despite progress since Eliza (1966), even advanced LLMs (e.g., GPT-4) struggle with medical data. This study presents a system combining knowledge embedding and transformers. It includes a knowledge understanding layer and an answer generation layer. Tested on the MedQA dataset, it achieved 82.92% accuracy, outperforming GPT-4’s 71.07%. The results demonstrate the system’s ability to deliver accurate and ethical answers. This integrated method improves response speed and quality. Future work will enhance precision, support patient interaction, and integrate multimodal data for improved healthcare query processing.

Article Details

Journal PLoS ONE
Volume / Issue Vol. 20, Issue 8
Published August 18, 2025
Pages e0329606
ISSN 1932-6203
Publisher Public Library of Science

Journal Info

PLoS ONE

Public Library of Science

ISSN: 1932-6203 Open Access Health Sciences

Authors (4)

X

Xiang Zhu

Hefei National Research Center for Physical Sciences at the Microscale, CAS Center for Excellence in Quantum Information and Quantum Physics, and New Cornerstone Science Laboratory

M

Mustaqeem Khan

A

Abdelmalik Taleb-Ahmed

A

Alice Othmani