ADCY4 inhibits cAMP-induced growth of breast cancer by inactivating FAK/AKT and ERK signaling but is frequently silenced by DNA methylation

Guangrui Pan; Mingquan Huang; Shaozhi Fu; Yu Wang; Lijia He; Bin Wu; Jinping Yang; Sheng Lin; Yu Fan

doi:10.1038/s41598-025-06294-1

ADCY4 inhibits cAMP-induced growth of breast cancer by inactivating FAK/AKT and ERK signaling but is frequently silenced by DNA methylation

G Guangrui Pan M Mingquan Huang S Shaozhi Fu Y Yu Wang L Lijia He B Bin Wu J Jinping Yang S Sheng Lin (Department of Emergency Medicine, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University) Y Yu Fan

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Article Details

Journal Scientific Reports

Volume / Issue Vol. 15, Issue 1

Published July 01, 2025

DOI 10.1038/s41598-025-06294-1

ISSN 2045-2322

Publisher Nature Portfolio

Journal Info

Scientific Reports

Nature Portfolio

ISSN: 2045-2322 Open Access Life Sciences

Authors (9)

G

Guangrui Pan

M

Mingquan Huang

S

Shaozhi Fu

Y

Yu Wang

L

Lijia He

B

Bin Wu

J

Jinping Yang

S

Sheng Lin

Department of Emergency Medicine, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University

Y

Yu Fan

ADCY4 inhibits cAMP-induced growth of breast cancer by inactivating FAK/AKT and ERK signaling but is frequently silenced by DNA methylation

Article Details

Journal Info

Authors (9)

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