ACSS2 drives senescence-associated secretory phenotype by limiting purine biosynthesis through PAICS acetylation

L Li Yang J Jianwei You X Xincheng Yang R Ruishu Jiao J Jie Xu Y Yue Zhang W Wen Mi L Lingzhi Zhu Y Youqiong Ye R Ruobing Ren (Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Fudan University) D Delin Min M Meilin Tang L Li Chen F Fuming Li P Pingyu Liu

Article Details

Volume / Issue Vol. 16, Issue 1
Published February 28, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (15)

L

Li Yang

J

Jianwei You

X

Xincheng Yang

R

Ruishu Jiao

J

Jie Xu

Y

Yue Zhang

W

Wen Mi

L

Lingzhi Zhu

Y

Youqiong Ye

R

Ruobing Ren

Shanghai Key Laboratory of Metabolic Remodeling and Health, Institute of Metabolism and Integrative Biology, Shanghai Xuhui Central Hospital, Zhongshan-Xuhui Hospital, Fudan University

D

Delin Min

M

Meilin Tang

L

Li Chen

F

Fuming Li

P

Pingyu Liu