Abstract 5733 Generation of synthetic circular supercoiled DNA (scsDNA) by cyclic heteroduplex thermostable ligation assembly (CHTLA): a scalable alternative to bacterial plasmid production in therapeutic development workflows

H Hedyeh Zamani X Xiang Li C Charles Bieberich

Article Details

Volume / Issue Vol. 302, Issue 5
Published May 01, 2026
Pages 112609
ISSN 0021-9258
Publisher Elsevier BV

Journal Info

Journal of Biological Chemistry

Elsevier BV

ISSN: 0021-9258 Open Access Life Sciences

Authors (3)

H

Hedyeh Zamani

X

Xiang Li

C

Charles Bieberich