AAV-delivered engineered suppressor tRNA rescues visual function in mice with an inherited retinal disease

C Chengda Ren (Department of Ophthalmology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China) L Li Song M Ming Hu X Xiu Jin L Licong Liang (Department of Ophthalmology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China) F Fanfei Liu (Department of Ophthalmology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China) J Jing Su J Jiamei Fu Y Yiliu Yang (Department of Ophthalmology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China) M Man Liu Q Qiuxia Xu X Xiaoyi Wu M Min Luo (College of Life Sciences, Anhui Normal University) Q Qin Ye Q Qiqi Li Y Yifang An M Manjun Li K Kaiqin She (Department of Ophthalmology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China) Y Yuquan Wei (State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University) F Fang Lu (Center for Functional Nanomaterials) Y Yang Yang

Article Details

Volume / Issue Vol. 16, Issue 1
Published December 17, 2025
ISSN 2041-1723
Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (21)

C

Chengda Ren

Department of Ophthalmology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China

L

Li Song

M

Ming Hu

X

Xiu Jin

L

Licong Liang

Department of Ophthalmology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China

F

Fanfei Liu

Department of Ophthalmology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China

J

Jing Su

J

Jiamei Fu

Y

Yiliu Yang

Department of Ophthalmology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China

M

Man Liu

Q

Qiuxia Xu

X

Xiaoyi Wu

M

Min Luo

College of Life Sciences, Anhui Normal University

Q

Qin Ye

Q

Qiqi Li

Y

Yifang An

M

Manjun Li

K

Kaiqin She

Department of Ophthalmology, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, China

Y

Yuquan Wei

State Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University

F

Fang Lu

Center for Functional Nanomaterials

Y

Yang Yang