A Single-Vesicle Electroanalytical Approach Uncovers Deficits of Vesicular Acetylcholine Content in Alzheimer’s Disease

Y Yuhang Jiang (Xiamen University , , ,) L Luyao Liu (State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications) M Meiping Xiong (State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications) W Weiyu Liu (State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications) H Haixin Wang (State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications) Y Yuying Liu (State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications) L Lijiao Cao (State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications) J Junlan Zhou (State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications) C Chuqi Li (State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications) C Chao Yuan (Department of Preventive Dentistry) L Lanqun Mao (College of Chemistry) X Xianchan Li (State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications)

Article Details

Volume / Issue Vol. 148, Issue 15
Published April 22, 2026
Pages 15848-15858
ISSN 0002-7863
Publisher American Chemical Society

Journal Info

Journal of the American Chemical Society

American Chemical Society

ISSN: 0002-7863 Physical Sciences

Authors (12)

Y

Yuhang Jiang

Xiamen University , , ,

L

Luyao Liu

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications

M

Meiping Xiong

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications

W

Weiyu Liu

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications

H

Haixin Wang

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications

Y

Yuying Liu

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications

L

Lijiao Cao

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications

J

Junlan Zhou

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications

C

Chuqi Li

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications

C

Chao Yuan

Department of Preventive Dentistry

L

Lanqun Mao

College of Chemistry

X

Xianchan Li

State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, Beijing Key Laboratory of Carbohydrate Intelligent Manufacture and Functional Applications