A recurrent pathogenic BRCA2 truncating variant reveals a role for BRCA2-PCAF complex in modulating NF-κB-driven transcription

Anna Minello; Jesus Gomez-Escudero; Sreerama Chaitanya Sridhara; Charlotte Martin; Elodie Girard; Juan C. Cañas; Yasin Memari; Maria Rose Bustos; Antonio Galarreta; Virginie Boucherit; Evgeny Imyanitov; Sigridur Klara Bodvarsdottir; Sylvain Baulande; Anne Vincent-Salomon; Nicolas Servant; Matthias Altmeyer; Stefan Sigurdsson; Dominique Stoppa-Lyonnet; Serena Nik-Zainal; Aura Carreira

doi:10.1038/s41467-025-67209-2

A recurrent pathogenic BRCA2 truncating variant reveals a role for BRCA2-PCAF complex in modulating NF-κB-driven transcription

A Anna Minello J Jesus Gomez-Escudero S Sreerama Chaitanya Sridhara C Charlotte Martin E Elodie Girard J Juan C. Cañas Y Yasin Memari M Maria Rose Bustos A Antonio Galarreta V Virginie Boucherit E Evgeny Imyanitov S Sigridur Klara Bodvarsdottir S Sylvain Baulande A Anne Vincent-Salomon N Nicolas Servant M Matthias Altmeyer S Stefan Sigurdsson D Dominique Stoppa-Lyonnet S Serena Nik-Zainal A Aura Carreira

Download PDF View Original

APA MLA Chicago BibTeX RIS

Article Details

Journal Nature Communications

Volume / Issue Vol. 16, Issue 1

Published December 10, 2025

DOI 10.1038/s41467-025-67209-2

ISSN 2041-1723

Publisher Nature Portfolio

Journal Info

Nature Communications

Nature Portfolio

ISSN: 2041-1723 Open Access Life Sciences

Authors (20)

A

Anna Minello

J

Jesus Gomez-Escudero

S

Sreerama Chaitanya Sridhara

C

Charlotte Martin

E

Elodie Girard

J

Juan C. Cañas

Y

Yasin Memari

M

Maria Rose Bustos

A

Antonio Galarreta

V

Virginie Boucherit

E

Evgeny Imyanitov

S

Sigridur Klara Bodvarsdottir

S

Sylvain Baulande

A

Anne Vincent-Salomon

N

Nicolas Servant

M

Matthias Altmeyer

S

Stefan Sigurdsson

D

Dominique Stoppa-Lyonnet

S

Serena Nik-Zainal

A

Aura Carreira

A recurrent pathogenic BRCA2 truncating variant reveals a role for BRCA2-PCAF complex in modulating NF-κB-driven transcription

Article Details

Journal Info

Authors (20)

Related Articles from this Journal

Synthesis of adaptive 15N-nitrosyl-Co7 nanocluster for electrocatalytic C–H functionalization

Pan-Ebolavirus nanoparticle vaccine provides protection in rodents from lethal infection by Zaire and Sudan viruses

Multi-population GWAS meta-analysis identifies bladder cancer susceptibility loci and highlights genetic regulation of smoking-related risk

Genome-wide annotation of human multi-nucleotide variants reveals widespread functional differences from single nucleotide variants

Allele-specific chromatin architecture shapes imprinted domains and coordinates a distal enhancer and antisense transcription at the mouse Mest-Copg2 domain